Evidence map›Paper›PMID 30401890›Full record

ArticleBritish journal of cancer2018

Association of symptoms and interval breast cancers in the mammography-screening programme: population-based matched cohort study.

Deependra Singh, Joonas Miettinen, Stephen Duffy, Nea Malila, Janne Pitkäniemi, Ahti Anttila

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in British journal of cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 24 citations in OpenAlex.

  1. Racial and Ethnic Variation in Diagnostic Mammography Performance among Women Reporting a Breast Lump.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Deependra SinghMass Screening Registry, Finnish Cancer Registry, FI-00130, Helsinki, Finland. deependra.singh@cancer.fi.
Joonas MiettinenMass Screening Registry, Finnish Cancer Registry, FI-00130, Helsinki, Finland.
Stephen DuffyWolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London, England.
Nea MalilaMass Screening Registry, Finnish Cancer Registry, FI-00130, Helsinki, Finland.
Janne PitkäniemiMass Screening Registry, Finnish Cancer Registry, FI-00130, Helsinki, Finland.
Ahti AnttilaMass Screening Registry, Finnish Cancer Registry, FI-00130, Helsinki, Finland.
Finnish Cancer Registry · FIQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe assessed the association between symptoms reported at breast cancer screening visits and interval cancers (ICs) in a prospective manner.

methodsThis population-based matched cohort study uses data of the Finnish National Breast Cancer Screening Programme that invites women aged 50-69 years old during 1992-2012. Subjects who attended screening with symptoms were matched with asymptomatic reference cohorts based on age at screening visit, year of invitation, number of invited visits and municipality of invitation. The primary outcome was ICs.

resultsWomen with a lump had a threefold (hazard ratio 3.7, 95% confidence interval (CI) 3.0-4.6) risk of ICs and a higher risk (hazard ratio 1.7, 95% CI 1.4 to 2.0) at the subsequent visit compared with those without a lump. The fatal interval cancer risk increased by 0.39 per 1000 screens with a lump. The cumulative incidences of interval cancer increased within a month of a mammography-negative visit with a lump and after about 6 months of the visit with retraction or nipple discharge.

conclusionWomen with breast symptoms have a clearly increased risk of interval breast cancer after the screening visit. Our findings indicate the need for different screening strategies in symptomatic women.

Indexed as

AgedBreast NeoplasmsCohort StudiesFemaleHumansMammographyMiddle Aged

Identifiers

PMID30401890
PMCPMC6265247
OpenAlexW4247397648

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.