Evidence map›Paper›PMID 30401875›Full record

ArticleScientific reports2018

Multilocus sequence typing of Candida albicans isolates from the oral cavities of patients undergoing haemodialysis.

Yan-Bing Gong, Bo Jin, He Qi, Rong Zhang, Xiu-Ying Zhang, Ping Yuan, Tong-Xiang Zhao, Xing-Hua Geng, Min Zhang, Jian-Ling Zheng

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Multilocus sequence typing ofOne health (Amsterdam, Netherlands) · 2025
    Article
  3. Article
  4. Article
  5. International journal of molecular sciences · 2025
    Article
  6. Article
  7. Molecular epidemiology ofFrontiers in veterinary science · 2023
    Article
  8. Article
  9. Article
  10. A Predominance of Clade 17Frontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan-Bing GongDepartment of Science Research, Peking University Shougang Hospital, Beijing, 100144, China. gongyanbing@bjmu.edu.cn.ORCID http://orcid.org/0000-0001-8896-3765
Bo JinDepartment of Clinical Laboratory, Peking University First Hospital, Beijing, 100034, China.
He QiDepartment of Medical Biotechnology, Medical Sciences Institute of Liaoning, Shenyang, Liaoning Province, 110101, China.
Rong ZhangDepartment of Oral Medicine, Peking University Shougang Hospital, Beijing, 100144, China.
Xiu-Ying ZhangDepartment of Medical Record, Peking University Shougang Hospital, Beijing, 100144, China.
Ping YuanDepartment of Science Research, Peking University Shougang Hospital, Beijing, 100144, China.
Tong-Xiang ZhaoDepartment of Science Research, Peking University Shougang Hospital, Beijing, 100144, China.
Xing-Hua GengDepartment of Nephrology, Peking University Shougang Hospital, Beijing, 100144, China.
Min ZhangDepartment of Nephrology, Rehabilitation Hospital of Capital Medical University, Beijing, 100044, China. 1274834875@qq.com.
Jian-Ling ZhengDepartment of Medical Biotechnology, Medical Sciences Institute of Liaoning, Shenyang, Liaoning Province, 110101, China. shenyangzheng@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluates the prevalence, diversity, and genetic profiles of Candida albicans isolates recovered from the oral cavities of haemodialysis patients. Oral swab samples were obtained from haemodialysis patients (n = 126) and healthy control subjects (n = 233) and Candida species were characterised. There was no significant difference between the haemodialysis and control groups in the prevalence of yeast carriers (23.6% vs. 31.0%, respectively) or C. albicans carriers (19.8% vs. 21.0%, respectively). C. albicans was the most populous species in both cohorts, followed by C. parapsilosis. C. parapsilosis and C. glabrata were more prevalent in the haemodialysis group than in the control group (C. parapsilosis 5.6% vs. 0.9% and C. glabrata 3.2% vs. 0.4%, respectively; P < 0.05). C. albicans isolates were analysed by multilocus sequence typing and the results were used to construct a phylogenetic tree. Most haemodialysis isolates were placed into Clade 4 (20.0%) and Clade 19 (16.0%) and most control isolates into Clade 8 (17%) and Clade 4 (14.9%). Differences in the strain abundance in each clade were not statistically significant between the two groups. Moreover, there was no significant association between the health status or diagnosis and either the sequence types or clades.

Indexed as

Multilocus Sequence TypingRenal DialysisAdultAgedAged, 80 and overBiodiversityCandida albicansFemaleHumansMaleMiddle AgedMouth

Identifiers

PMID30401875
PMCPMC6219599

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.