Evidence map›Paper›PMID 30401874›Full record

ReviewNature communications2018

A deadly dance: the choreography of host-pathogen interactions, as revealed by single-cell technologies.

Pratip K Chattopadhyay, Mario Roederer, Diane L Bolton

Abstract readReview
In one paragraph

Review in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Artificial Intelligence Methods in Infection Biology Research.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  5. Editorial: Emerging mechanisms of host-pathogen interactions and immune responses.Frontiers in cellular and infection microbiology · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. A Roadmap for the Human Gut Cell Atlas.Nature reviews. Gastroenterology & hepatology · 2023
    Review
  14. Review
  15. Single cell multiomic analysis of T cell exhaustion in vitro.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2022
    Article
  16. Transcriptome Architecture of Osteoblastic Cells Infected WithFrontiers in cellular and infection microbiology · 2022
    Article
  17. Review
  18. Review
  19. Single-cell RNA sequencing in cancer research.Journal of experimental & clinical cancer research : CR · 2021
    Review
  20. A Cytometrist's Guide to Coordinating and Performing Effective COVID-19 Research.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pratip K ChattopadhyayPrecision Immunology, NYU Langone Health, New York, 10016, NY, USA.
Mario RoedererImmunoTechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, 20892, MD, USA.ORCID http://orcid.org/0000-0001-7448-7040
Diane L BoltonUS Military HIV Research Program, Henry M. Jackson Foundation, Walter Reed Army Institute of Research, Silver Spring, 20910, MD, USA. dbolton@hivresearch.org.

Funding

Functional And Phenotypic Characterization Of T Cells In ManZIAAI005021 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROEDERER, MARIO · 2009 to 2022
$14.4M
Development Of Flow Cytometric Technologies For Immune AssaysZIAAI005020 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ROEDERER, MARIO · 2009 to 2019
$9.6M
U.S. Department of Defense (DOD) W81XWH-07-2-0067
6 · The paper itself

Abstract

Pathogens have numerous mechanisms by which they replicate within a host, who in turn responds by developing innate and adaptive immune countermeasures to limit disease. The advent of high-content single-cell technologies has facilitated a greater understanding of the properties of host cells harboring infection, the host's pathogen-specific immune responses, and the mechanisms pathogens have evolved to escape host control. Here we review these advances and argue for greater inclusion of higher resolution single-cell technologies into approaches for defining immune evasion mechanisms by pathogens.

Indexed as

Flow CytometryHigh-Throughput Nucleotide SequencingHost-Pathogen InteractionsImmune EvasionImmunity, InnateInclusion BodiesInfectionsLaser Capture MicrodissectionNucleic AcidsSingle-Cell AnalysisTranscriptomeNucleic Acids

Identifiers

PMID30401874
PMCPMC6219517

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.