Evidence map›Paper›PMID 30401782›Full record

ArticlemBio2018

The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein.

Krystal A Fontaine, Kristoffer E Leon, Mir M Khalid, Sakshi Tomar, David Jimenez-Morales, Mariah Dunlap, Julia A Kaye, Priya S Shah, Steve Finkbeiner, Nevan J Krogan and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. The consequence of simultaneous and sequential coinfections ofFrontiers in cellular and infection microbiology · 2026
    Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Krystal A Fontaine *Gladstone Institutes, San Francisco, California, USA.
Kristoffer E Leon *Gladstone Institutes, San Francisco, California, USA.
Mir M KhalidGladstone Institutes, San Francisco, California, USA.
Sakshi TomarGladstone Institutes, San Francisco, California, USA.
David Jimenez-MoralesGladstone Institutes, San Francisco, California, USA.
Mariah DunlapGladstone Institutes, San Francisco, California, USA.
Julia A KayeGladstone Institutes, San Francisco, California, USA.
Priya S ShahQuantitative Biosciences Institute (QBI) and Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California, USA.
Steve FinkbeinerGladstone Institutes, San Francisco, California, USA.
Nevan J KroganGladstone Institutes, San Francisco, California, USA.
Melanie OttGladstone Institutes, San Francisco, California, USA melanie.ott@gladstone.ucsf.edu.
Gladstone Institutes · USUniversity of California, San Francisco · USQuantitative BioSciences · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007618 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANDERSON, MARK S · 1985 to 2020
$29.6M
Rare Variant Whole Genome Analysis and iPSC Validation of Putative Genetic Modifiers of Huntington DiseaseR37NS101996 · NINDS · J. DAVID GLADSTONE INSTITUTES · PI FINKBEINER, STEVEN M · 2017 to 2023
$4.4M
Role of Lipid Droplets in Hepatitis C Virus InfectionR01AI097552 · NIAID · J. DAVID GLADSTONE INSTITUTES · PI OTT, MELANIE MARIA · 2014 to 2018
$2.4M
Quantitative mapping of interactions between dengue virus and its hostsF32AI112262 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHAH, PRIYA SHIRISH · 2014 to 2016
$113k
NIAID NIH HHS F32 AI112262NIAID NIH HHS R01 AI097552NIGMS NIH HHS T32 GM007618NINDS NIH HHS R37 NS101996
6 · The paper itself

Abstract

Zika virus (ZIKV) infection of neural progenitor cells (NPCs)

Indexed as

Nonsense Mediated mRNA DecayCapsid ProteinsDown-RegulationHumansNeural Stem CellsProteasome Endopeptidase ComplexRNA HelicasesRNA InterferenceTrans-ActivatorsZika VirusZika Virus InfectionCapsid ProteinsProteasome Endopeptidase ComplexRNA HelicasesTrans-ActivatorsUPF1 protein, humannonsense-mediated mRNA decay pathwayvirus-host interactionsZika virus

Identifiers

PMID30401782
PMCPMC6222128
OpenAlexW2949922540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.