Evidence map›Paper›PMID 30401576›Full record

ArticleEuropean journal of internal medicine2019

An international perspective on hospitalized patients with viral community-acquired pneumonia.

Dejan Radovanovic, Giovanni Sotgiu, Mateja Jankovic, Padukudru Anand Mahesh, Pedro Jorge Marcos, Mohamed I Abdalla, Marta Francesca Di Pasquale, Andrea Gramegna, Silvia Terraneo, Francesco Blasi and 5 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in European journal of internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
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  5. Observational
  6. Myosteatosis predicting risk of transition to severe COVID-19 infection.Clinical nutrition (Edinburgh, Scotland) · 2022
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  9. Extremely Old Patients Hospitalized in Internal Medicine: What about Their Anemia?Mediterranean journal of hematology and infectious diseases · 2021
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  12. Observational
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 20 institutions in 24 countries.

Dejan RadovanovicDepartment of Biomedical and Clinical Sciences (DIBIC), University of Milan, Section of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milan, Italy.
Giovanni SotgiuClinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Medicine, University of Sassari, Sassari, Italy.
Mateja JankovicSchool of Medicine, University of Zagreb, Department for Respiratory Diseases Jordanovac, University Hospital Centre Zagreb, Croatia.
Padukudru Anand MaheshDepartment of Pulmonary Medicine, JSS Medical College, JSS Academy of Higher Education and Research, Mysore, India.
Pedro Jorge MarcosDirección de Procesos Asistenciales, Servicio de Neumología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complejo Hospitalario Universitario de A Coruña (CHUAC), Estructura Organizativa de Xestion Integrada (EOXI) de A Coruña, SERGAS, Universidade da Coruña (UDC), A Coruña, Spain.
Mohamed I AbdallaSouth Texas Veterans Health Care System and University of Texas Health, San Antonio, TX, USA.
Marta Francesca Di PasqualeDepartment of Pathophysiology and Transplantation, University of Milan, Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Andrea GramegnaDepartment of Pathophysiology and Transplantation, University of Milan, Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Silvia TerraneoDepartment of Health Sciences, University of Milan, Milan, Italy; Department of Health Sciences, University of Milan, Respiratory Unit, San Paolo Hospital, Milan, Italy.
Francesco BlasiDepartment of Pathophysiology and Transplantation, University of Milan, Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Pierachille SantusDepartment of Biomedical and Clinical Sciences (DIBIC), University of Milan, Section of Respiratory Diseases, Ospedale L. Sacco, ASST Fatebenefratelli-Sacco, Milan, Italy.
Stefano AlibertiDepartment of Pathophysiology and Transplantation, University of Milan, Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: stefano.aliberti@unimi.it.
Luis F ReyesDepartment of Microbiology, Universidad de La Sabana, Chia, Colombia.
Marcos I RestrepoSouth Texas Veterans Health Care System and University of Texas Health, San Antonio, TX, USA.
GLIMP Study Group
University Hospital Centre Zagreb · HRAmerican College of Chest Physicians · USRegionshospitalet Viborg · DKJSS Academy of Higher Education and Research · INUniversity of Sassari · ITUniversity of Milan · ITTongji University · CNUniversity of Kinshasa · CDDélégation Paris 7 · FRFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITRoskilde Sygehus · DKUniversity Hospital St. Marina · BGAl-Azhar University · EGPeking University · CNJimma University · ETThe University of Texas Health Science Center at San Antonio · USUniversidad de La Sabana · COUniversidade da Coruña · ESUniversity of Douala · CMKomfo Anokye Teaching Hospital · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWho should be tested for viruses in patients with community acquired pneumonia (CAP), prevalence and risk factors for viral CAP are still debated. We evaluated the frequency of viral testing, virus prevalence, risk factors and treatment coverage with oseltamivir in patients admitted for CAP.

methodsSecondary analysis of GLIMP, an international, multicenter, point-prevalence study of hospitalized adults with CAP. Testing frequency, prevalence of viral CAP and treatment with oseltamivir were assessed among patients who underwent a viral swab. Univariate and multivariate analysis was used to evaluate risk factors.

results553 (14.9%) patients with CAP underwent nasal swab. Viral CAP was diagnosed in 157 (28.4%) patients. Influenza virus was isolated in 80.9% of cases. Testing frequency and viral CAP prevalence were inhomogeneous across the participating centers. Obesity (OR 1.59, 95%CI: 1.01-2.48; p = 0.043) and need for invasive mechanical ventilation (OR 1.62, 95%CI: 1.02-2.56; p = 0.040) were independently associated with viral CAP. Prevalence of empirical treatment with oseltamivir was 5.1%.

conclusionIn an international scenario, testing frequency for viruses in CAP is very low. The most common cause of viral CAP is Influenza virus. Obesity and need for invasive ventilation represent independent risk factors for viral CAP. Adherence to recommendations for treatment with oseltamivir is poor.

Indexed as

AgedAged, 80 and overAntiviral AgentsCommunity-Acquired InfectionsCross-Sectional StudiesDatabases, FactualFemaleHospitalizationHumansInfluenza, HumanInternationalityLogistic ModelsMaleMedication AdherenceMiddle AgedOseltamivirAntiviral AgentsOseltamivirCommunity acquired pneumoniaInfluenzaOseltamivirTestingViral pneumoniaViral swab

Identifiers

PMID30401576
PMCPMC7127340
OpenAlexW2898956895

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.