Evidence map›Paper›PMID 30400976›Full record

ArticleParasites & vectors2018

Insights into malaria transmission among Anopheles funestus mosquitoes, Kenya.

Edwin O Ogola, Ulrike Fillinger, Isabella M Ondiba, Jandouwe Villinger, Daniel K Masiga, Baldwyn Torto, David P Tchouassi

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 78 citations in OpenAlex.

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  12. Insecticide resistance intensity inCurrent research in parasitology & vector-borne diseases · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Edwin O OgolaInternational Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya.
Ulrike FillingerInternational Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya.
Isabella M OndibaSchool of Biological Sciences, University of Nairobi, Nairobi, Kenya.
Jandouwe VillingerInternational Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya.
Daniel K MasigaInternational Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya.
Baldwyn TortoInternational Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya.
David P TchouassiInternational Centre of Insect Physiology and Ecology (icipe), Nairobi, Kenya. dtchouassi@icipe.org.ORCID http://orcid.org/0000-0001-9910-4704
International Centre of Insect Physiology and Ecology · KEUniversity of Nairobi · KE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost malaria vectors belong to species complexes. Sibling species often exhibit divergent behaviors dictating the measures that can be deployed effectively in their control. Despite the importance of the Anopheles funestus complex in malaria transmission in sub-Saharan Africa, sibling species have rarely been identified in the past and their vectoring potential remains understudied.

methodsWe analyzed 1149 wild-caught An. funestus (senso lato) specimens from 21 sites in Kenya, covering the major malaria endemic areas including western, central and coastal areas. Indoor and outdoor collection tools were used targeting host-seeking and resting mosquitoes. The identity of sibling species, infection with malaria Plasmodium parasites, and the host blood meal sources of engorged specimens were analyzed using PCR-based and sequencing methods.

resultsThe most abundant sibling species collected in all study sites were Anopheles funestus (59.8%) and Anopheles rivulorum (32.4%) among the 1062 successfully amplified specimens of the An. funestus complex. Proportionally, An. funestus dominated in indoor collections whilst An. rivulorum dominated in outdoor collections. Other species identified were Anopheles leesoni (4.6%), Anopheles parensis (2.4%), Anopheles vaneedeni (0.1%) and for the first time in Kenya, Anopheles longipalpis C (0.7%). Anopheles funestus had an overall Plasmodium infection rate of 9.7% (62/636), predominantly Plasmodium falciparum (59), with two infected with Plasmodium ovale and one with Plasmodium malariae. There was no difference in the infection rate between indoor and outdoor collections. Out of 344 An. rivulorum, only one carried P. falciparum. We also detected P. falciparum infection in two non-blood-fed An. longipalpis C (2/7) which is the first record for this species in Kenya. The mean human blood indices for An. funestus and An. rivulorum were 68% (93/136) and 64% (45/70), respectively, with feeding tendencies on a broad host range including humans and domestic animals such as cow, goat, sheep, chicken and pig.

conclusionsOur findings underscore the importance of active surveillance through application of molecular approaches to unravel novel parasite-vector associations possibly contributed by cryptic species with important implications for effective malaria control and elimination.

Indexed as

Feeding BehaviorAnimalsAnophelesDisease VectorsFemaleKenyaMalariaMalaria, FalciparumMosquito VectorsPlasmodium falciparumPolymerase Chain ReactionAnopheles funestus groupAnopheles longipalpis CEntomological surveillanceKenyaMalaria parasite transmissionMolecular approaches

Identifiers

PMID30400976
PMCPMC6219006
OpenAlexW2900060701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.