ArticleLipids in health and disease2018
Impact of dyslipidemia on 24-h urine composition in adults without urolithiasis.
Article in Lipids in health and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 24 citations in OpenAlex.
- A randomized clinical trial evaluating the short-term results of ureteral stent encrustation in urolithiasis patients undergoing ureteroscopy: micro-computed tomography evaluation.Scientific reports · 2021Trial
- Retrospective evaluation of lipiduria in urine from 140 dogs and 74 cats.Journal of veterinary internal medicine · 2026Article
- ZJU index and prevalence of kidney stones in US adults: evidence for a threshold association from NHANES 2007-2018.Translational andrology and urology · 2026Article
- 24-hour urine chemistry shows higher stone formation risk after malabsorptive than restrictive type bariatric surgery.Scientific reports · 2026Article
- The atherogenic index of plasma increases the risk of incident kidney stones: a nested case-control study in Chinese adults.Renal failure · 2025Article
- Exploring the Impact of Urinary Metal Exposure on Blood Lipid Profiles in Chinese Adults: Mediating Roles of Health-Related Indicators.Journal of the American Heart Association · 2025Article
- Inverted V-shaped association between atherogenic index of plasma and kidney stone risk: results from NHANES 2011-2018.Translational andrology and urology · 2025Article
- Association between the Fatty Liver Index, Metabolic Dysfunction-Associated Steatotic Liver Disease, and the Risk of Kidney Stones.Kidney & blood pressure research · 2025Article
- Association between the neutrophil-to-high-density lipoprotein cholesterol ratio with kidney stone risk: a cross-sectional study.Frontiers in endocrinology · 2025Article
- Relationship between the atherogenic index of plasma and the prevalence of kidney stones: insights from a population-based cross-sectional study.Renal failure · 2024Article
- A cross-sectional analysis of the relationship between the non-high density to high density lipoprotein cholesterol ratio (NHHR) and kidney stone risk in American adults.Lipids in health and disease · 2024Article
- The association of visceral adiposity index with the risk of kidney stone and kidney stone recurrence.BMC nephrology · 2023Article
- Association between urinary sodium and circulating lipid levels: a Mendelian randomization study.Frontiers in endocrinology · 2023Article
- Association between hypertension and 24-h urine composition in adults without urolithiasis in China.World journal of urology · 2021Article
- Dietary vinegar prevents kidney stone recurrence via epigenetic regulations.EBioMedicine · 2019Article
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9 authors at 4 institutions in 1 country.
Funding
Abstract
purposesTo evaluate the influence of dyslipidemia on 24-h urine composition in adults who were non-stone formers (NF).
methodsSamples for 24-h urine composition were analyzed from 584 NF adults without urolithiasis in a national six-city-based epidemiologic study. The samples were divided into groups based on total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), and low-density lipoprotein (LDL). The groups were compared based on demographic data and each component of 24-h urinalysis.
resultsThe numbers of participants in high TG, high TC, high LDL, and low HDL were 106, 175, 147, and 59, respectively. The high TG group had increased urinary excretions of oxalate [mean difference (MD) = 0.032 mmol, 95% confidence interval (CI): 0.000-0.065] and potassium (MD = 4.298 mmol, 95%CI: 0.182-8.414). Increased urinary excretion of calcium (MD = 0.531 mmol, 95%CI: 0.061-1.001), sodium (MD = 41.561 mmol, 95%CI: 9.179-73.942), and chloride (MD = 45.209 mmol, 95%CI: 12.118-78.299) were found in the high TC group. Interestingly, the high LDL group had a decreased urinary excretion of calcium (MD = - 0.573 mmol, 95%CI: -1.048 to - 0.097), oxalate (MD = - 0.038 mmol, 95%CI: -0.07 to - 0.006), sodium (MD = - 53.285 mmol, 95%CI: -85.823 to - 20.748), and chloride (MD = - 55.809 mmol, 95%CI: -89.035 to - 22.583). Increased urinary excretions of citrate (MD = 0.455 mmol, 95%CI: 0.076-0.835) and magnesium (MD = 0.697 mmol, 95%CI: 0.244-1.149) were found in the low HDL group.
conclusionsThe present study first investigated the effects of dyslipidemia on 24-h urinalysis in NF adults. Of note, high LDL and low HDL were found to be adversely related to kidney stone formation. However, people with high TG and high TC should be cautious of getting kidney stones.
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