ArticleTrials2018
DELTA
Article in Trials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 40 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Controlled Trial of Peer Support Workers in the Emergency Department for People Experiencing Homelessness in the Niagara Region of Ontario, Canada
Effectiveness of Using Upright Versus Lithotomy Birthing Position on Maternal and Newborn Outcomes: A Quasi Experimental Study
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of sample size determination in Bayesian randomized clinical trials: full Bayesian methods are rarely used.BMC medical research methodology · 2026Pooled it
- Estimates of the mean difference in orthopaedic randomized trials: obligatory yet obscure.BMC medical research methodology · 2021Pooled it
- Trial
- Trial
- Trial
- Trial
- Letter to the Editor "Perioperative Music Therapy Enhances Pain Management and Sleep Quality in Patients Aged 50-70 Years Undergoing Total Knee Arthroplasty: A Randomized Controlled Trial"[Letter].Journal of pain research · 2026Article
- Statistical Gems and Cautions From the Statistical Advisory Board of Clinical Oral Implants Research.Clinical oral implants research · 2025Article
- The mixed-meal tolerance test as an appetite assay: methodological and practical considerations.International journal of obesity (2005) · 2025Review
- Effects of Dietary Fiber Supplementation on Gut Microbiota and Bowel Function in Healthy Adults: A Randomized Controlled Trial.Microorganisms · 2025Article
- Disparity between statistical significance and clinical importance in published randomised controlled trials: a methodological study.BMJ open · 2025Article
- Protocol Development for Investigator-Sponsored Clinical Studies.Clinical and translational science · 2025Article
- Society for Immunotherapy of Cancer (SITC) consensus statement on essential biomarkers for immunotherapy clinical protocols.Journal for immunotherapy of cancer · 2025Article
- Conceptualizing meaningful between-group difference in change over time: a demonstration of possible viewpoints.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Interpretation of statistical findings in randomised trials: a survey of statisticians using thematic analysis of open-ended questions.BMC medical research methodology · 2024Article
- Article
- Review
- Are web-based stress management interventions effective as an indirect treatment for depression? An individual participant data meta-analysis of six randomised trials.BMJ mental health · 2024Article
- Article
- Robot-mediated impairment-oriented and task-specific training on upper limb post stroke: feasibility and preliminary effects on physical function and quality of life.Frontiers in neurology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
Abstract
backgroundA key step in the design of a RCT is the estimation of the number of participants needed in the study. The most common approach is to specify a target difference between the treatments for the primary outcome and then calculate the required sample size. The sample size is chosen to ensure that the trial will have a high probability (adequate statistical power) of detecting a target difference between the treatments should one exist. The sample size has many implications for the conduct and interpretation of the study. Despite the critical role that the target difference has in the design of a RCT, the way in which it is determined has received little attention. In this article, we summarise the key considerations and messages from new guidance for researchers and funders on specifying the target difference, and undertaking and reporting a RCT sample size calculation. This article on choosing the target difference for a randomised controlled trial (RCT) and undertaking and reporting the sample size calculation has been dual published in the BMJ and BMC Trials journals
methodsThe DELTA RESULTS AND DISCUSSION: The key messages from the DELTA
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.