Evidence map›Paper›PMID 30400907›Full record

ArticleReproductive health2018

Psychopathology is associated with reproductive health risk in European adolescents.

Pietro Gambadauro, Vladimir Carli, Camilla Wasserman, Gergö Hadlaczky, Marco Sarchiapone, Alan Apter, Judit Balazs, Julio Bobes, Romuald Brunner, Doina Cosman and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Reproductive health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Dysmenorrhea and Adolescent Mental Health: A School-Based Cross-Sectional Study.BJOG : an international journal of obstetrics and gynaecology · 2025
    Article
  3. Article
  4. Risk management during times of health uncertainty in Spain: A qualitative analysis of ethical challenges.Risk analysis : an official publication of the Society for Risk Analysis · 2025
    Article
  5. Review
  6. Article
  7. Retrospective review of rates of sexually transmitted and blood-borne infection (STBBI) testing in provincial corrections facilities in Newfoundland and Labrador.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Adolescent Emotion Regulation and Parent-Child Discussions about Sexual Behaviors.International journal of sexual health : official journal of the World Association for Sexual Health · 2021
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 13 institutions in 13 countries.

Pietro GambadauroNational Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Department of Learning, Informatics, Management and Ethics (LIME), Karolinska Institutet, 171 77, Stockholm, Sweden. gambadauro@gmail.com.
Vladimir CarliNational Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Department of Learning, Informatics, Management and Ethics (LIME), Karolinska Institutet, 171 77, Stockholm, Sweden.
Camilla WassermanNational Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Department of Learning, Informatics, Management and Ethics (LIME), Karolinska Institutet, 171 77, Stockholm, Sweden.
Gergö HadlaczkyNational Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Department of Learning, Informatics, Management and Ethics (LIME), Karolinska Institutet, 171 77, Stockholm, Sweden.
Marco SarchiaponeDepartment of Medicine and Health Science, University of Molise, 86100, Campobasso, Italy.
Alan ApterSchneider Children's Medical Center of Israel, Tel Aviv University, Tel Aviv, Israel.
Judit BalazsVadaskert Child Psychiatric Hospital and Outpatient Clinic, Budapest, 1021, Hungary.
Julio BobesDepartment of Psychiatry, University of Oviedo, CIBERSAM School of Medicine, Julian Claveria 6 - 3°, 33006, Oviedo, Spain.
Romuald BrunnerDepartment of Child & Adolescent Psychiatry, Center for Psychosocial Medicine, University of Heidelberg, Blumenstrasse 8, D-69115, Heidelberg, Germany.
Doina CosmanClinical Psychology Department, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Christian HaringDepartment for Psychiatry and Psychotherapy B, State Hospital Hall in Tyrol, Tirol-kliniken, Milser Straße 10, A- 6060, Hall, Austria.
Christina W HovenDepartment of Child and Adolescent Psychiatry, Columbia University-New York State Psychiatric Institute, New York, USA.
Miriam IosueDepartment of Medicine and Health Science, University of Molise, 86100, Campobasso, Italy.
Michael KaessDepartment of Child & Adolescent Psychiatry, Center for Psychosocial Medicine, University of Heidelberg, Blumenstrasse 8, D-69115, Heidelberg, Germany.
Jean Pierre KahnDepartment of Psychiatry and Clinical Psychology, CHRU de NANCY and Pôle 6, Centre Psychothérapique de Nancy-Laxou, Université de Lorraine, NANCY, France.
Elaine McMahonNational Suicide Research Foundation, University College Cork, Cork, Ireland.
Vita PostuvanSlovene Center for Suicide Research, Andrej Marusic Institute, University of Primorska, Muzejski trg 2, 6000, Koper, Slovenia.
Airi VärnikEstonian-Swedish Mental Health & Suicidology Institute, Ctr. Behav. & Hlth. Sci, Tallinn University, Tallinn, Estonia.
Danuta WassermanNational Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Department of Learning, Informatics, Management and Ethics (LIME), Karolinska Institutet, 171 77, Stockholm, Sweden.
Karolinska Institutet · SEHeidelberg University · DEUniversity of Molise · ITCentro de Investigación Biomédica en Red de Salud Mental · ESEötvös Loránd University · HUEstonian-Swedish Mental Health and Suicidology Institute · EEIuliu Hațieganu University of Medicine and Pharmacy · RONational Suicide Research Foundation · IENew York State Psychiatric InstituteSchneider Children's Medical Center · ILTirol Kliniken · ATUniversité de Lorraine · FRUniversity of Primorska · SI

Funding

European Union FP7; HEALTH-F2-2009-223091
6 · The paper itself

Abstract

backgroundReproductive and mental health are key domains of adolescent wellbeing but possible interrelationships are poorly understood. This cross-sectional study evaluated the association between psychopathology and reproductive health risk among European adolescents.

methodsA structured self-report questionnaire was delivered to 12,395 pupils of 179 randomly selected schools in 11 European countries within the EU funded "Saving and Empowering Young Lives in Europe" (SEYLE) project. The questionnaire included items about sexual initiation and reproductive health risk factors, such as number of sexual partners, frequency of condom use, and pregnancy involvement. Psychopathology was evaluated with validated instruments and/or ad-hoc questions.

resultsOf 11,406 respondents (median age 15; interquartile range [IQR] 14-15; 57% females), 18.8% reported sexual initiation. Sixty percent of them also reported at least one reproductive risk factor. Sexual initiation was significantly more common among pupils older than 15 years (38% versus 13.2% younger pupils) and males (21.3% versus 16.9% females). It was also more common among pupils with depression (age/sex-adjusted odds ratio [aOR] 1.871), anxiety (aOR 2.190), severe suicidal ideation (aOR 2.259), self-injurious behaviour (aOR 2.892), and suicide attempts (aOR 3.091). These associations were particularly strong among pupils ≤15 years old and, for overt psychopathology, among pupils with low non-sexual risk behaviour profile and females. Depression (aOR 1.937), anxiety (aOR 2.282), severe suicidal ideation (aOR 2.354), self-injurious behaviour (aOR 3.022), and suicide attempts (aOR 3.284) were associated with higher reproductive health risk, defined by an increasing number of coexisting reproductive risk factors.

conclusionsThese findings suggest an alignment between mental and reproductive health risk and support the value of cross-domain collaboration in adolescent health. The association between psychopathology and reproductive health risk, as well as its variations with age, sex, and associated risk behaviours, should be considered when designing health-promoting or disease-preventing interventions for adolescents.

Indexed as

AdolescentAdolescent BehaviorAge FactorsAnxietyCross-Sectional StudiesDepressionEuropeFemaleHealth SurveysHumansMaleMental DisordersReproductive HealthRisk FactorsRisk-TakingSexual BehaviorAdolescenceBehaviourMental healthPsychopathologyReproductive healthSexual initiationSEYLE study

Identifiers

PMID30400907
PMCPMC6220505
OpenAlexW2900294452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.