Evidence map›Paper›PMID 30400888›Full record

ArticleBMC veterinary research2018

Highly sensitive electrochemical biosensor based on redox - active monolayer for detection of anti-hemagglutinin antibodies against swine-origin influenza virus H1N1 in sera of vaccinated mice.

Edyta Mikuła, Cristiane Erdmann Silva, Edyta Kopera, Konrad Zdanowski, Jerzy Radecki, Hanna Radecka

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

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  12. Review-Chemical and Biological Sensors for Viral Detection.Journal of the Electrochemical Society · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Edyta MikułaInstitute of Animal Reproduction and Food Research of Polish Academy of Sciences, Tuwima 10, 10-748, Olsztyn, Poland.
Cristiane Erdmann SilvaUniversidade Estadual de Ponta Grossa - UEPG, Setor de Ciências Exatas e da Terra, Departamento de Química, Av. Carlos Cavalcanti, 4748, CEP 84030-900, Ponta Grossa/ PR, Brazil.
Edyta KoperaInstitute of Biochemistry and Biophysics of Polish Academy of Sciences, Pawińskiego 5a, 02-106, Warsaw, Poland.
Konrad ZdanowskiInstitute of Biochemistry and Biophysics of Polish Academy of Sciences, Pawińskiego 5a, 02-106, Warsaw, Poland.
Jerzy RadeckiInstitute of Animal Reproduction and Food Research of Polish Academy of Sciences, Tuwima 10, 10-748, Olsztyn, Poland.
Hanna RadeckaInstitute of Animal Reproduction and Food Research of Polish Academy of Sciences, Tuwima 10, 10-748, Olsztyn, Poland. h.radecka@pan.olsztyn.pl.ORCID http://orcid.org/0000-0002-9394-2325
InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences · PLRCA (United States) · USUniversidade Estadual de Ponta Grossa · BRUniversity of Siedlce · PL

Funding

Narodowe Centrum Badań i Rozwoju PBS2/A7/14/ 2014
6 · The paper itself

Abstract

backgroundIn this work, we report an electrochemical biosensor for the detection of anti-hemagglutinin antibodies against the swine virus H1N1 present in mice sera immunized with mixture of His

resultsThis analytical device was able to detect the antibodies present in vaccinated mice sera diluted from 1 × 10

conclusionsThe unprecedented sensitivity of described biosensor is much better than widely use ELISA test and other analytical methods for determination of antibodies against the influenza A viruses. It has been proved that redox active DPM-Cu (II) monolayer is a universal platform suitable for stable and oriented immobilization of any His-tagged sensing elements. Thus, this universal layer could be a base of numerous analytical devices suitable for detection of antibodies against different viruses.

Indexed as

AnimalsAntibodies, ViralBiosensing TechniquesFemaleHemagglutinin Glycoproteins, Influenza VirusInfluenza A Virus, H1N1 SubtypeInfluenza VaccinesMiceMice, Inbred BALB COrthomyxoviridae InfectionsOxidation-ReductionPotentiometrySwineSwine DiseasesAntibodies, ViralHemagglutinin Glycoproteins, Influenza VirusInfluenza VaccinesAvian swine virusDetection of antibodies in mice seraElectrochemical biosensorHistidine-tagged hemagglutinin monomer

Identifiers

PMID30400888
PMCPMC6218974
OpenAlexW2899825319

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.