SynthesisBMC endocrine disorders2018
Bisphenol A exposure and type 2 diabetes mellitus risk: a meta-analysis.
Synthesis in BMC endocrine disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 50 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Personalized Mobile Intervention to Reduce Exposure to Endocrine Disrupting Chemicals (EDCs) in Women of Child-Bearing Age and Their Partners
A Personalized Digital Intervention Program to Reduce Exposure to Endocrine Disrupting Chemicals Among a Child-Bearing Age Cohort
Minority-focused Environmental Health Education and Tracking (MEET) Pilot Study
Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity
Who cites it
50 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- An Umbrella Review of Meta-Analyses Evaluating Associations between Human Health and Exposure to Major Classes of Plastic-Associated Chemicals.Annals of global health · 2024Pooled it
- Ultra-Processed Food Intake Is Associated with Non-Alcoholic Fatty Liver Disease in Adults: A Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- Bisphenol A exposure and abnormal glucose tolerance during pregnancy: systematic review and meta-analysis.Environmental science and pollution research international · 2021Pooled it
- Beyond medication adherence: bisphenol exposure and its relationship with good glycemic control in type 2 diabetes.Acta diabetologica · 2026Article
- Emerging role of microplastics and nanoplastics in children's health.Pediatric research · 2026Review
- Analysis of Paraben and Bisphenol A Exposure in Relation to Food Intake Levels and Health Risk Assessments in the Taiwanese Population.Journal of food science · 2025Article
- Evolution of hepatology practice in Mexico and Latin America: From biochemical markers to genomic medicine.World journal of hepatology · 2025Review
- Endocrine-disrupting chemicals exposure: cardiometabolic health risk in humans.Cardiovascular diabetology · 2025Review
- A comprehensive review/expert statement on environmental risk factors of cardiovascular disease.Cardiovascular research · 2025Review
- A Review of the Evidence of the Toxicity of Chemical Substances Included in the European Union Ambient Air Quality and Drinking Water Directives: Perspectives for Health Impact Assessments.Environment & health (Washington, D.C.) · 2025Review
- Article
- Soil and water pollution and cardiovascular disease.Nature reviews. Cardiology · 2025Review
- Environmental and social determinants of cardiovascular risk in women with type 2 diabetes: a life-course perspective.Frontiers in endocrinology · 2025Review
- Endocrine disruptors, insulin resistance, and diabetes.Turkish journal of medical sciences · 2025Review
- Article
- A Close Relationship Between Ultra-Processed Foods and Adiposity in Adults in Southern Italy.Nutrients · 2024Article
- Endocrine disrupting chemicals and obesity prevention: scoping review.Journal of health, population, and nutrition · 2024Article
- Environmental Sustainability of Food Environments: Development and Application of a Framework in 4 cities in South Asia.Current developments in nutrition · 2024Article
- Creation and validation of a NOVA scored picture set to evaluate ultra-processed foods.Appetite · 2024Article
- Developmental programming: An exploratory analysis of pancreatic islet compromise in female sheep resulting from gestational BPA exposure.Molecular and cellular endocrinology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundThis meta-analytic study explored the relationship between the risk of type 2 diabetes mellitus (T2DM) and bisphenol A concentrations.
methodsThe Embase and Medline (PubMed) databases were searched, using relevant keywords, for studies published between 1980 and 2018. A total of 16 studies, twelve cross-sectional, two case-control and one prospective, were included in the meta-analysis. The odds ratio (OR) and its 95% confidence interval (CI) were determined across the sixteen studies. The OR and its 95% CI of diabetes associated with bisphenol A were estimated using both fixed-effects and random-effects models.
resultsA total of 41,320 subjects were included. Fourteen of the sixteen studies included in the analysis provided measurements of urine bisphenol A levels and two study provided serum bisphenol A levels. Bisphenol A concentrations in human bio-specimens showed positive associations with T2DM risk (OR 1.28, 95% CI 1.14, 1.44). A sensitivity analysis indicated that urine bisphenol A concentrations were positively associated with T2DM risk (OR 1.20, 95% CI 1.09, 1.31).
conclusionsThis meta-analysis indicated that Bisphenol A exposure is positively associated with T2DM risk in humans.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.