ArticleBMC emergency medicine2018
Reduction in the IL-6 level at 24 h after admission to the intensive care unit is a survival predictor for Vietnamese patients with sepsis and septic shock: a prospective study.
Article in BMC emergency medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- IL-6 Baseline Values and Dynamic Changes in Predicting Sepsis Mortality: A Systematic Review and Meta-Analysis.Biomolecules · 2025Pooled it
- Article
- Article
- Article
- Characteristics of Interleukin-6 Signaling in Elective Cardiac Surgery-A Prospective Cohort Study.Journal of clinical medicine · 2022Article
- Diagnostic and Prognostic Value of Interleukin-6 in Emergency Department Sepsis Patients.Infection and drug resistance · 2022Article
- Article
- Article
- A 2-Biomarker Model Augments Clinical Prediction of Mortality in Melioidosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Effects of Neutrophil-to-Lymphocyte Ratio Combined With Interleukin-6 in Predicting 28-Day Mortality in Patients With Sepsis.Frontiers in immunology · 2021Observational
- Multiplexed cytokine detection using electrochemical point-of-care sensing device towards rapid sepsis endotyping.Biosensors & bioelectronics · 2021Review
- Temperature Trajectory Subphenotypes Correlate With Immune Responses in Patients With Sepsis.Critical care medicine · 2020Observational
- Observational
- Study on the correlation and clinical significance of T-lymphocyte Subsets, IL-6 and PCT in the severity of patients with sepsis.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSepsis and septic shock are common problems in intensive care units (ICUs). The mortality of patients with sepsis or septic shock is high. We investigated if reduction in the serum concentration of the cytokines tumor necrosis factor α, interleukin (IL)-6 and IL-10, and the rate of change in the IL-6 level at 24 h after ICU admission were survival predictors for patients with sepsis and septic shock in a Vietnamese population.
methodsThis was a prospective study conducted at an ICU in Cho Ray Hospital, Vietnam, from October 2014 to October 2016. Patients diagnosed with sepsis or septic shock using validated international guidelines were enrolled. Plasma samples were collected upon (T
resultsA total of 123 patients were enrolled. The concentration (in pg/mL) of IL-6 at T
conclusionsOur findings suggested that a reduction in the IL-6 level of ≥86% at 24 h from ICU admission is a survival predictor for patients with sepsis and septic shock in our population.
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Registered trials
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