Evidence map›Paper›PMID 30400730›Full record

ArticleGut and liver2019

Distinction between Chronic Enteropathy Associated with the

Shunichi Yanai, Satoko Yamaguchi, Shotaro Nakamura, Keisuke Kawasaki, Yosuke Toya, Noriyuki Yamada, Makoto Eizuka, Noriyuki Uesugi, Junji Umeno, Motohiro Esaki and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Gut and liver, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. BiallelicFrontiers in endocrinology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. A Novel Chronic Enteropathy Associated withKorean journal of radiology · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Shunichi YanaiDivision of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Satoko YamaguchiDivision of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Shotaro NakamuraDivision of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Keisuke KawasakiDivision of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Yosuke ToyaDivision of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Noriyuki YamadaDivision of Molecular Diagnostic Pathology, Department of Pathology, Iwate Medical University, Morioka, Japan.
Makoto EizukaDivision of Molecular Diagnostic Pathology, Department of Pathology, Iwate Medical University, Morioka, Japan.
Noriyuki UesugiDivision of Molecular Diagnostic Pathology, Department of Pathology, Iwate Medical University, Morioka, Japan.
Junji UmenoDepartment of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Motohiro EsakiDepartment of Endoscopic Diagnostic and Therapeutics, Saga University, Saga, Japan.
Eiko OkimotoDepartment of Gastroenterology and Hepatology, Shimane University School of Medicine, Izumo, Japan.
Shunji IshiharaDepartment of Gastroenterology and Hepatology, Shimane University School of Medicine, Izumo, Japan.
Tamotsu SugaiDivision of Molecular Diagnostic Pathology, Department of Pathology, Iwate Medical University, Morioka, Japan.
Takayuki MatsumotoDivision of Gastroenterology, Department of Internal Medicine, Iwate Medical University, Morioka, Japan.
Iwate Medical University · JPShimane University · JPKyushu University · JPSaga University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/Aims: We recently identified recessive mutations in the solute carrier organic anion transporter family member 2A1 gene ( Methods: Immunohistochemical staining for SLCO2A1 was performed with a polyclonal antibody, HPA013742, on gastroduodenal tissues obtained by endoscopic biopsy from four patients with CEAS and 29 patients with CD. Results: The expression of SLCO2A1 was observed in one of four patients (25%) with CEAS and in all 29 patients (100%) with CD (p<0.001). The three patients with CEAS without SLCO2A1 expression had a homozygous splice-site mutation in Conclusions: Immunohistochemical staining for SLCO2A1 in gastroduodenal tissues obtained by endoscopic biopsy is considered useful for the distinction of CEAS from CD.

Indexed as

AdolescentAdultAgedBiopsyChildChronic DiseaseCrohn DiseaseDiagnosis, DifferentialDuodenumEndoscopy, GastrointestinalExonsFemaleGastric MucosaHumansImmunohistochemistryIntestinal DiseasesOrganic Anion TransportersRNA Splice SitesSLCO2A1 protein, humanChronic enteropathy associated with SLCO2A1 geneCrohn diseaseImmunohistochemistrySLCO2A1

Identifiers

PMID30400730
PMCPMC6347011
OpenAlexW2899956214

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.