Evidence map›Paper›PMID 30400640›Full record

ArticleNutrients2018

Isolation and Characterization of Potentially Probiotic Bacterial Strains from Mice: Proof of Concept for Personalized Probiotics.

Larissa S Celiberto, Roseli Aparecida Pinto, Elizeu Antonio Rossi, Bruce A Vallance, Daniela C U Cavallini

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Larissa S CelibertoDepartment of Food and Nutrition, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil. larissasbaglia@gmail.com.ORCID 0000-0001-9057-9041
Roseli Aparecida PintoDepartment of Food and Nutrition, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil. rosely@fcfar.unesp.br.
Elizeu Antonio RossiDepartment of Food and Nutrition, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil. elizeurossi@yahoo.com.br.
Bruce A VallanceDivision of Gastroenterology, Department of Pediatrics, BC Children's Hospital and the University of British Columbia, Vancouver, BC V5Z 4H4, Canada. bvallance@cw.bc.ca.
Daniela C U CavalliniDepartment of Food and Nutrition, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, SP, Brazil. cavallinidc@fcfar.unesp.br.
Universidade Estadual Paulista (Unesp) · BRUniversity of British Columbia · CA

Funding

Canadian Institutes of Health Research PJT 148846 and 159528Crohn's and Colitis Canada -Fundação de Amparo à Pesquisa do Estado de São Paulo 2014/15129-1
6 · The paper itself

Abstract

Modulation of the gut microbiota through the use of probiotics has been widely used to treat or prevent several intestinal diseases. However, inconsistent results have compromised the efficacy of this approach, especially in severe conditions such as inflammatory bowel disease (IBD). The purpose of our study was to develop a personalized probiotic strategy and assess its efficacy in a murine model of intestinal inflammation. Commensal bacterial strains were isolated from the feces of healthy mice and then administered back to the host as a personalized treatment in dextran sodium sulfate (DSS)-induced colitis. Colonic tissues were collected for histological analysis and to investigate inflammatory markers such as

Indexed as

Gastrointestinal MicrobiomeProbioticsAnimalsBifidobacteriumBiomarkersColitisColonCytokinesDextran SulfateDisease Models, AnimalDrug Resistance, Multiple, BacterialInflammationInflammatory Bowel DiseasesIntestinesLactobacillusMaleBiomarkersCytokinesDextran SulfateMalondialdehydePeroxidaseBifidobacteriumcolitisIBDLactobacillusmicrobiotamicrobiota biobankpersonalized probiotic

Identifiers

PMID30400640
PMCPMC6266017
OpenAlexW2900417627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.