Evidence map›Paper›PMID 30400509›Full record

ArticleMicromachines2017

Rethinking the Design of Low-Cost Point-of-Care Diagnostic Devices.

Faith W Kimani, Samuel M Mwangi, Benjamin J Kwasa, Abdi M Kusow, Benjamin K Ngugi, Jiahao Chen, Xinyu Liu, Rebecca Cademartiri, Martin M Thuo

Abstract read
In one paragraph

Article in Micromachines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Evolution of technology and disparities in antimicrobial stewardship: a narrative review.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Review
  2. Article
  3. Article
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  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Faith W KimaniKiambu District Hospital, Kiambu 00900, Kenya. kimani.faith@gmail.com.
Samuel M MwangiSchool of Public Health, Kenyatta University, Nairobi 00100, Kenya. mwangi.samuel@ku.ac.ke.
Benjamin J KwasaDepartment of Aerospace Engineering, Iowa State University, Ames, IA 50011, USA. bjkwasa@iastate.edu.
Abdi M KusowDepartment of Sociology, Iowa State University, Ames, IA 00100, USA. kusow@iastate.edu.
Benjamin K NgugiDepartment of Information Systems and Operations Management, Suffolk University, Boston, MA 02108, USA. bngugi@suffolk.edu.
Jiahao ChenDepartment of Material Science and Engineering, Iowa State University, Ames, IA 50011, USA. jiahao@iastate.edu.
Xinyu LiuDepartment of Mechanical Engineering and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, ON M5S 3G8, Canada. xyliu@mie.utoronto.ca.
Rebecca CademartiriDepartment of Mechanical Engineering and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, ON M5S 3G8, Canada. rcademar@iastate.edu.
Martin M ThuoDepartment of Mechanical Engineering and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, ON M5S 3G8, Canada. mthuo@iastate.edu.ORCID 0000-0003-3448-8027

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reducing the global diseases burden requires effective diagnosis and treatment. In the developing world, accurate diagnosis can be the most expensive and time-consuming aspect of health care. Healthcare cost can, however, be reduced by use of affordable rapid diagnostic tests (RDTs). In the developed world, low-cost RDTs are being developed in many research laboratories; however, they are not being equally adopted in the developing countries. This disconnect points to a gap in the design philosophy, where parameterization of design variables ignores the most critical component of the system, the point-of-use stakeholders (e.g., doctors, nurses and patients). Herein, we demonstrated that a general focus on reducing cost (i.e., "low-cost"), rather than efficiency and reliability is misguided by the assumption that poverty reduces the value individuals place on their well-being. A case study of clinicians in Kenya showed that "zero-cost" is a low-weight parameter for point-of-use stakeholders, while reliability and standardization are crucial. We therefore argue that a user-driven, value-addition systems-engineering approach is needed for the design of RDTs to enhance adoption and translation into the field.

Indexed as

diagnosticshealth carelow costrapid diagnosticstechnology adoptionvalue-added design

Identifiers

PMID30400509
PMCPMC6190021

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.