ArticleMicromachines2017
Milling Positive Master for Polydimethylsiloxane Microfluidic Devices: The Microfabrication and Roughness Issues.
Article in Micromachines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Augmented 3D Printing for Multiscale Microphysiological Systems.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Interfacial Engineering-Free Microfluidics: Toward a Mild and Cost-Effective Strategy for Surfactant- and Demulsifier-Free Hydrogel Microsphere Fabrication.Micromachines · 2025Article
- Low Cost, Ease-of-Access Fabrication of Microfluidic Devices Using Wet Paper Molds.Micromachines · 2022Article
- Fabrication of Polymer Microfluidics: An Overview.Polymers · 2022Review
- Time-efficient fabrication method for 3D-printed microfluidic devices.Scientific reports · 2022Article
- A Systematic Approach for Developing 3D High-Quality PDMS Microfluidic Chips Based on Micromilling Technology.Micromachines · 2021Article
- Research Progress of Microtransfer Printing Technology for Flexible Electronic Integrated Manufacturing.Micromachines · 2021Review
- A Low-Cost 3-in-1 3D Printer as a Tool for the Fabrication of Flow-Through Channels of Microfluidic Systems.Micromachines · 2021Article
- A novel abrasive water jet machining technique for rapid fabrication of three-dimensional microfluidic components.Biomicrofluidics · 2020Article
- Micro-Macro: Selective Integration of Microfeatures Inside Low-Cost Macromolds for PDMS Microfluidics Fabrication.Micromachines · 2019Article
- A Milled Microdevice to Advance Glia-Mediated Therapies in the Adult Nervous System.Micromachines · 2019Article
- Editorial for the Special Issue on Polymer Based MEMS and Microfabrication.Micromachines · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
We provide a facile and low-cost method (F-L) to fabricate a two-dimensional positive master using a milling technique for polydimethylsiloxane (PDMS)-based microchannel molding. This method comprises the following steps: (1) a positive microscale master of the geometry is milled on to an acrylic block; (2) pre-cured PDMS is used to mold the microscale positive master; (3) the PDMS plate is peeled off from the master and punctured with a blunt needle; and (4) the PDMS plate is O₂ plasma bonded to a glass slide. Using this technique, we can fabricate microchannels with very simple protocols quickly and inexpensively. This method also avoids breakage of the end mill (ϕ = 0.4 mm) of the computerized numerical control (CNC) system when fabricating the narrow channels (width < 50 µm). The prominent surface roughness of the milled bottom-layer could be overcomed by pre-cured PDMS with size trade-off in design. Finally, emulsion formation successfully demonstrates the validity of the proposed fabrication protocol. This work represents an important step toward the use of a milling technique for PDMS-based microfabrication.
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