Evidence map›Paper›PMID 30400444›Full record

ArticleMicromachines2017

Analytical Formulation of the Electric Field Induced by Electrode Arrays: Towards Automated Dielectrophoretic Cell Sorting.

Vladimir Gauthier, Aude Bolopion, Michaël Gauthier

Abstract read
In one paragraph

Article in Micromachines, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vladimir GauthierFEMTO-ST Institute, AS2M Department, Univ Bourgogne Franche-Comté, CNRS, 24 rue Alain Savary, 25000 Besancon, France. vladimir.gauthier@femto-st.fr.ORCID 0000-0002-9467-0165
Aude BolopionFEMTO-ST Institute, AS2M Department, Univ Bourgogne Franche-Comté, CNRS, 24 rue Alain Savary, 25000 Besancon, France. aude.bolopion@femto-st.fr.
Michaël GauthierFEMTO-ST Institute, AS2M Department, Univ Bourgogne Franche-Comté, CNRS, 24 rue Alain Savary, 25000 Besancon, France. michael.gauthier@femto-st.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dielectrophoresis is defined as the motion of an electrically polarisable particle in a non-uniform electric field. Current dielectrophoretic devices enabling sorting of cells are mostly controlled in open-loop applying a predefined voltage on micro-electrodes. Closed-loop control of these devices would enable to get advanced functionalities and also more robust behavior. Currently, the numerical models of dielectrophoretic force are too complex to be used in real-time closed-loop control. The aim of this paper is to propose a new type of models usable in this framework. We propose an analytical model of the electric field based on Fourier series to compute the dielectrophoretic force produced by parallel electrode arrays. Indeed, this method provides an analytical expression of the electric potential which decouples the geometrical factors (parameter of our system), the voltages applied on electrodes (input of our system), and the position of the cells (output of our system). Considering the Newton laws on each cell, it enables to generate easily a dynamic model of the cell positions (output) function of the voltages on electrodes (input). This dynamic model of our system is required to design the future closed-loop control law. The predicted dielectrophoretic forces are compared to a numerical simulation based on finite element model using COMSOL software. The model presented in this paper enables to compute the dielectrophoretic force applied to a cell by an electrode array in a few tenths of milliseconds. This model could be consequently used in future works for closed-loop control of dielectrophoretic devices.

Indexed as

cell sortingdielectrophoresiselectrode arrayfourier seriesmicromanipulation

Identifiers

PMID30400444
PMCPMC6189918

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.