ArticleBehavioral sciences (Basel, Switzerland)2018
Elevated Levels of Serum IL-17A in Community-Dwelling Women with Higher Depressive Symptoms.
Article in Behavioral sciences (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 33 citations in OpenAlex.
- Effects of Adolescent-Focused Integrated Social Protection on Depression: A Pragmatic Cluster-Randomized Controlled Trial of Tanzania's Cash Plus Intervention.American journal of epidemiology · 2022Trial
- Relationship between objective sleep efficiency and psychological distress in middle-aged and older Japanese: Results by work in the Shika study.BMC psychology · 2026Article
- The association between spatiotemporal coupling of default mode network and behaviors is specifically modulated by peripheral inflammation in major depressive disorder.BMC psychiatry · 2026Article
- Altered subgenual anterior cingulate cortex connectivity in psoriasis patients with depression: a resting-state fMRI case-control study.Annals of general psychiatry · 2026Article
- Review
- Neuroinflammation-A Crucial Factor in the Pathophysiology of Depression-A Comprehensive Review.Biomolecules · 2025Review
- Serum TNFα and IL-17A levels may predict increased depressive symptoms: findings from the Shika Study cohort project in Japan.BioPsychoSocial medicine · 2024Article
- Downregulated NPAS4 in multiple brain regions is associated with major depressive disorder.Scientific reports · 2023Article
- Relationship between Vitamin Intake and Resilience Based on Sex in Middle-Aged and Older Japanese Adults: Results of the Shika Study.Nutrients · 2022Article
- Stress-induced despair behavior develops independently of the Ahr-RORγt axis in CD4 + cells.Scientific reports · 2022Article
- Depression and Obesity in Patients With Psoriasis and Psoriatic Arthritis: Is IL-17-Mediated Immune Dysregulation the Connecting Link?Frontiers in immunology · 2021Review
- Is Interleukin 17 (IL-17) Expression A Common Point in the Pathogenesis of Depression and Obesity?Journal of clinical medicine · 2020Article
- Rheumatoid Arthritis: The Impact of Mental Health on Disease: A Narrative Review.Rheumatology and therapy · 2020Review
- Pro- and anti-inflammatory properties of interleukin (IL6) in vitro: relevance for major depression and for human hippocampal neurogenesis.The international journal of neuropsychopharmacology · 2020Article
- The Role of Gut Mucins in the Etiology of Depression.Frontiers in behavioral neuroscience · 2020Review
- Interleukin-17A in Egyptian leprosy patients: a clinical, genetic, and biochemical study.Anais brasileiros de dermatologiaArticle
- The Extract of Acanthopanacis Cortex Relieves the Depression-Like Behavior and Modulates IL-17 Signaling in Chronic Mild Stress-Induced Depressive Mice.Dose-response : a publication of International Hormesis SocietyArticle
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7 authors at 3 institutions in 1 country.
Funding
Abstract
Recent studies indicate that patients with depression have increased concentrations of serum pro-inflammatory cytokines. However, studies of IL-17 and studies on community-dwellers are few. The purpose of this study was to investigate serum cytokine levels, especially IL-17A, among subjects with high and low depressive symptoms of a general population. The participants comprised 20 female community-dwellers aged 40 years or older who contributed to a Shika study in Ishikawa, Japan. Ten participants who showed higher and ten who showed lower depressive symptoms among 208 females assessed by the Japanese version of the Centre for Epidemiologic Studies Depression Scale (CES-D) were selected for this study. Serum samples were analyzed for TNF-alpha, IL-6, IL-10, IL-12, and IL-17A using a multiplex Luminex analysis. For the comparison between the high and low depressive groups statistically, linear regression analyses were applied. The serum level of IL-17A was significantly higher among the high depressive participants (
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