Evidence map›Paper›PMID 30400306›Full record

ArticleNutrients2018

Carotenoid Content in Human Colostrum is Associated to Preterm/Full-Term Birth Condition.

Ana A O Xavier, Elena Díaz-Salido, Isabel Arenilla-Vélez, Josefa Aguayo-Maldonado, Juan Garrido-Fernández, Javier Fontecha, Alicia Sánchez-García, Antonio Pérez-Gálvez

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

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  13. Observational
  14. Optical properties of human milk.Biomedical optics express · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ana A O XavierDepartment of Food Phytochemistry, Instituto de la Grasa (CSIC), Campus Universitario, Building 46, 41013 Sevilla, Spain. anaaugustax@gmail.com.
Elena Díaz-SalidoUnidad de Neonatología, Hospital Virgen del Rocío, 41013 Sevilla, Spain. elenam.diaz.sspa@juntadeandalucia.es.
Isabel Arenilla-VélezUnidad de Neonatología, Hospital Virgen del Rocío, 41013 Sevilla, Spain. Isaareni@yahoo.es.
Josefa Aguayo-MaldonadoUnidad de Neonatología, Hospital Virgen del Rocío, 41013 Sevilla, Spain. pepaaguayo@gmail.com.ORCID 0000-0002-2323-5721
Juan Garrido-FernándezDepartment of Food Phytochemistry, Instituto de la Grasa (CSIC), Campus Universitario, Building 46, 41013 Sevilla, Spain. jgarrido@ig.csic.es.
Javier FontechaInstitute of Food Science Research (CSIC-UAM), 28049 Madrid, Spain. j.fontecha@csic.es.
Alicia Sánchez-GarcíaLaboratorio de Espectrometría de Masas, Instituto de la Grasa (CSIC), 41013 Sevilla, Spain. asangar@ig.csic.es.ORCID 0000-0002-7919-0614
Antonio Pérez-GálvezDepartment of Food Phytochemistry, Instituto de la Grasa (CSIC), Campus Universitario, Building 46, 41013 Sevilla, Spain. aperez@ig.csic.es.ORCID 0000-0001-6914-8378
Instituto de la Grasa · ESHospital Universitario Virgen del Rocío · ESInstituto de Investigación en Ciencias de la Alimentación · ES

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España AGL2013-42757-R and AGL2017-87884-R
6 · The paper itself

Abstract

Factors such as lactation stage and premature and small-for-gestational conditions could lead to great inter-individual variability in the carotenoid content of human milk. The aim was to analyze the carotenoid content in colostrum and mature milk of preterm (PT) and full-term (FT) mothers to establish whether they are significantly different and, if so, the stage of lactation when the differences are established. Samples of blood, colostrum, and mature milk were collected from Spanish donating mothers who gave birth to PT or FT infants. Carotenoids from serum and milk samples were analyzed by HPLC-atmospheric pressure chemical ionization (APCI)-MS. Quantitatively, colostrum from PT mothers presented lower total carotenoid content when compared to that from FT mothers. The only exception was lutein, where levels were not different. The transition from colostrum to mature milk makes observed differences in the carotenoid content disappear, since there were no variances between PT and FT groups for both individual and total carotenoid content. The premature birth condition affects the quantitative carotenoid composition of the colostrum but has no effect on the lutein content. This fact could be related to the significant role of this xanthophyll in the development of infant retina and feasibly to cognitive function.

Indexed as

Infant, PrematureLactationTerm BirthCarotenoidsColostrumEvaluation Studies as TopicFemaleGestational AgeHumansInfant, NewbornLuteinMilk, HumanXanthophyllsCarotenoidsLuteinXanthophyllsbreastfeedingcarotenescolostrumfull-term mothersluteinmature milknew-bornpreterm mothersxanthophylls

Identifiers

PMID30400306
PMCPMC6266713
OpenAlexW2899293078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.