Evidence map›Paper›PMID 30400299›Full record

ArticleMarine drugs2018

Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest.

Rosa Maria Vitale, Enrico D'Aniello, Stefania Gorbi, Andrea Martella, Cristoforo Silvestri, Maria Elisa Giuliani, Tariq Fellous, Alessandra Gentile, Marianna Carbone, Adele Cutignano and 12 more

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Foods (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Frontiers in chemistry · 2022
    Article
  10. Caulerpin MitigatesInternational journal of molecular sciences · 2021
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Effect of the algal alkaloid caulerpin on neuropeptide Y (NPY) expression in the central nervous system (CNS) of Diplodus sargus.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 5 institutions in 2 countries.

Rosa Maria VitaleInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. rmvitale@icb.cnr.it.
Enrico D'AnielloInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. enrico.daniello@szn.it.
Stefania GorbiDepartment of Life and Environmental Sciences, Polytechnic University of Marche, 60131 Ancona, Italy. s.gorbi@univpm.it.
Andrea MartellaInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. a.martella@lacdr.leidenuniv.nl.
Cristoforo SilvestriInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. cristoforo.silvestri.1@ulaval.ca.ORCID 0000-0001-5635-1545
Maria Elisa GiulianiDepartment of Life and Environmental Sciences, Polytechnic University of Marche, 60131 Ancona, Italy. m.e.giuliani@univpm.it.
Tariq FellousInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. tariq_fellous@hotmail.com.
Alessandra GentileInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. alessandra.gentile@mpi-bn.mpg.de.
Marianna CarboneInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. mcarbone@icb.cnr.it.
Adele CutignanoInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. acutignano@icb.cnr.it.
Laura GrausoInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. lagrauso@unina.it.
Laura MagliozziDepartment of Biology, University of Naples "Federico II", 80126 Naples, Italy. laura.magliozzi@unina.it.
Gianluca PoleseDepartment of Biology, University of Naples "Federico II", 80126 Naples, Italy. gianluca.polese@unina.it.ORCID 0000-0002-6322-7769
Biagio D'AnielloDepartment of Biology, University of Naples "Federico II", 80126 Naples, Italy. biagio.daniello@unina.it.
Fanny DefranouxInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. f.defranoux@icb.cnr.it.
Serena FellineThe National Interuniversity Consortium For Marine Sciences (CoNISMa), 00198 Rome, Italy. felline@conisma.it.
Antonio TerlizziDepartment of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, 80121 Naples, Italy. aterlizzi@units.it.ORCID 0000-0001-5968-4548
Antonio CalignanoDepartment of Pharmacy, University of Naples "Federico II", 80131 Naples, Italy. calignan@unina.it.
Francesco RegoliDepartment of Life and Environmental Sciences, Polytechnic University of Marche, 60131 Ancona, Italy. f.regoli@univpm.it.
Vincenzo Di MarzoInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. vdimarzo@icb.cnr.it.ORCID 0000-0002-1490-3070
Pietro AmodeoInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. pamodeo@icb.cnr.it.ORCID 0000-0002-6439-7575
Ernesto MolloInstitute of Biomolecular Chemistry, National Research Council of Italy, 80078 Pozzuoli, Italy. emollo@icb.cnr.it.ORCID 0000-0001-7379-1788
National Research Council · ITUniversity of Naples Federico II · ITMarche Polytechnic University · ITUniversity of Trieste · ITStazione Zoologica Anton Dohrn · IT

Funding

Ministero dell'Istruzione, dell'Università e della Ricerca PRIN 2012, CAULERFISH project
6 · The paper itself

Abstract

Although the chemical warfare between invasive and native species has become a central problem in invasion biology, the molecular mechanisms by which bioactive metabolites from invasive pests influence local communities remain poorly characterized. This study demonstrates that the alkaloid caulerpin (CAU)-a bioactive component of the green alga

Indexed as

Introduced SpeciesAnimalsBiological FactorsCaulerpaComputer SimulationEcotoxicologyFish DiseasesFood ChainIndolesLigandsModels, BiologicalPerciformesPeroxisome Proliferator-Activated ReceptorsBiological FactorscaulerpinIndolesLigandsPeroxisome Proliferator-Activated Receptorsbiological invasionsCaulerpa cylindraceacaulerpinMediterraneanmolecular interactionsPPAR

Identifiers

PMID30400299
PMCPMC6267082
OpenAlexW2899485458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.