Evidence map›Paper›PMID 30400292›Full record

SynthesisNutrients2018

The Role of Fiber in the Treatment of Functional Gastrointestinal Disorders in Children.

Cara Hannah Axelrod, Miguel Saps

2 registry-linked trialsOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04590846 nacompletednot on this mapstarted 2020, after this paper: background citation

The Effectiveness of a Caregiver-mediated Health Educational Intervention on Improving Constipation Among Primary School Children and the Knowledge and Attitude Toward Constipation Among Their Caregivers

TypeinterventionalSponsorAsia UniversityRan2020 to 2020Enrolled173ConditionsConstipationArmsConstipation Health Education Intervention Course, General Health Course
NCT05867550 phase4completednot on this mapstarted 2023, after this paper: background citation

To Compare the Efficacy of (Rifaximin + Mebeverine), (Rifaximin + Amitriptyline), and (Rifaximin + Psyllium Husk) in Irritable Bowel Syndrome Associated With Diarrhea

TypeinterventionalSponsorBahria UniversityRan2023 to 2023Enrolled162ConditionsIrritable Bowel Syndrome With DiarrheaArmsRifaximin 550 MG, Mebeverine 135 MG, Psyllium Husk, Amitriptyline Hydrochloride 25 MG
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
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  13. Article
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  15. Article
  16. Current treatment practice of functional abdominal pain disorders in children: A multicenter survey.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022
    Article
  17. Review
  18. Review
  19. Differences in dietary habits of people withWorld journal of clinical cases · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Cara Hannah AxelrodDivision of Pediatric Gastroenterology, Hepatology, and Nutrition, University of Miami Miller School of Medicine, Miami, FL 33136, USA. cxa630@med.miami.edu.
Miguel SapsDivision of Pediatric Gastroenterology, Hepatology, and Nutrition, University of Miami Miller School of Medicine, Miami, FL 33136, USA. msaps@med.miami.edu.
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We reviewed the available evidence on the role of fiber in the treatment of Functional Constipation (FC) and Irritable Bowel Syndrome (IBS) in children. The vast majority of toddlers and preschoolers do not consume enough fiber. Two of the most common reasons for consultation to a pediatric gastroenterology practice include FC and IBS. The North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (NASPGHAN) and the European Society of Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) guidelines state that the evidence does not support the use of fiber supplements in the treatment of FC in children, and the Rome IV criteria do not recommend an increase in fiber consumption, in children with IBS. Despite this, in general practice, it is commonly recommended that children who experience constipation and IBS to increase their fiber intake. We conducted a systematic review of the available evidence on the role of fiber in the treatment of FC and IBS in children. Thirteen full-text articles with a total of seven hundred and twenty-three pediatric participants were included in this review. Three clinical trials found positive effects of dietary fiber for the management of IBS. Nine out of ten trials found fiber to be either more effective than placebo, or just as effective as laxative treatment. Most studies on the use of fiber for the treatment of FC and IBS have shown its benefit. However, due to the heterogeneity in study design, length of treatment, outcome measures, and amount and type of fiber, we were unable to make a definitive recommendation supporting the use of fiber for the treatment of FC and IBS in children.

Indexed as

AdolescentChildChild, PreschoolConstipationDietary FiberGastrointestinal DiseasesHumansIrritable Bowel SyndromeRandomized Controlled Trials as TopicDietary Fiberabdominal painchildrenfiberfunctional constipationirritable bowel syndrome

Identifiers

PMID30400292
PMCPMC6267171
OpenAlexW2899412527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.