Evidence map›Paper›PMID 30400245›Full record

ArticleInternational journal of molecular sciences2018

Intravenous Delivery of

Shingo Nakamura, Masayuki Ishihara, Satoshi Watanabe, Naoko Ando, Masato Ohtsuka, Masahiro Sato

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. International journal of biological sciences · 2025
    Article
  2. Masitinib Inhibits Hepatitis A Virus Replication.International journal of molecular sciences · 2023
    Article
  3. Article
  4. Article
  5. Pharmaceutics · 2020
    Review
  6. Review
  7. In VivoInternational journal of molecular sciences · 2019
    Article
  8. RNA-guidedSynthetic biology (Oxford, England) · 2019
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shingo NakamuraDivision of Biomedical Engineering, National Defense Medical College Research Institute, Saitama 359-8513, Japan. snaka@ndmc.ac.jp.ORCID 0000-0001-6084-0958
Masayuki IshiharaDivision of Biomedical Engineering, National Defense Medical College Research Institute, Saitama 359-8513, Japan. ishihara@ndmc.ac.jp.
Satoshi WatanabeAnimal Genome Unit, Institute of Livestock and Grassland Science, National Agriculture and Food Research Organization (NARO), 2 Ikenodai, Tsukuba, Ibaraki 305-0901, Japan. kettle@affrc.go.jp.
Naoko AndoDivision of Biomedical Engineering, National Defense Medical College Research Institute, Saitama 359-8513, Japan. naoandokoro@gmail.com.
Masato OhtsukaDivision of Basic Medical Science and Molecular Medicine, School of Medicine, Tokai University, Kanagawa 259-1193, Japan. masato@is.icc.u-tokai.ac.jp.ORCID 0000-0002-6952-4238
Masahiro SatoSection of Gene Expression Regulation, Frontier Science Research Center, Kagoshima University, Kagoshima 890-8544, Japan. masasato@m.kufm.kagoshima-u.ac.jp.ORCID 0000-0003-1334-2950

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrodynamics-based gene delivery (HGD) is an efficient method for transfecting plasmid DNA into hepatocytes in vivo. However, the resulting gene expression is transient, and occurs in a non-tissue specific manner. The

Indexed as

Genetic TherapyAdministration, IntravenousAnimalsChickensDNA Transposable ElementsGene Transfer TechniquesHydrodynamicsIntegrasesLiverMaleMice, Inbred ICROrgan SpecificityRecombination, GeneticSerumCre recombinaseDNA Transposable ElementsIntegrasesCre/loxPdiphtheria toxin-A chainEGFPhepatic disorderhydrodynamics-based gene deliveryin vivo gene deliveryliverpiggyBac transposon

Identifiers

PMID30400245
PMCPMC6274756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.