Evidence map›Paper›PMID 30400165›Full record

ArticleMolecules (Basel, Switzerland)2018

Pentafluorosulfanyl-containing Triclocarban Analogs with Potent Antimicrobial Activity.

Eugènia Pujol, Núria Blanco-Cabra, Esther Julián, Rosana Leiva, Eduard Torrents, Santiago Vázquez

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Diarylureas: New Promising Small Molecules againstAntibiotics (Basel, Switzerland) · 2023
    Review
  5. Article
  6. Antimicrobial agents and chemotherapy · 2021
    Article
  7. The Different Facets of Triclocarban: A Review.Molecules (Basel, Switzerland) · 2021
    Review
  8. Article
  9. Review
  10. Beilstein journal of organic chemistry · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eugènia PujolLaboratori de Química Farmacèutica (Unitat Associada al CSIC), Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain. epujol@ub.edu.ORCID 0000-0003-1941-0539
Núria Blanco-CabraBacterial Infections and Antimicrobial Therapies, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Baldiri Reixac 15-21, 08028 Barcelona, Spain. nblanco@ibecbarcelona.eu.
Esther JuliánDepartament de Genètica i de Microbiologia, Facultat de Biociències, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain. esther.julian@uab.cat.ORCID 0000-0002-6558-3978
Rosana LeivaLaboratori de Química Farmacèutica (Unitat Associada al CSIC), Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain. rosana.leiva58@gmail.com.
Eduard TorrentsBacterial Infections and Antimicrobial Therapies, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology, Baldiri Reixac 15-21, 08028 Barcelona, Spain. etorrents@ibecbarcelona.eu.
Santiago VázquezLaboratori de Química Farmacèutica (Unitat Associada al CSIC), Facultat de Farmàcia i Ciències de l'Alimentació, and Institute of Biomedicine (IBUB), Universitat de Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain. svazquez@ub.edu.ORCID 0000-0002-9296-6026

Funding

Generalitat de Catalunya 2017 SGR 106Generalitat de Catalunya 2017 SGR 1079Ministerio de Economía, Industria y Competitividad, Gobierno de España BIO2015-63557-RMinisterio de Economía, Industria y Competitividad, Gobierno de España SAF2017-82771
6 · The paper itself

Abstract

Concerns have been raised about the long-term accumulating effects of triclocarban, a polychlorinated diarylurea widely used as an antibacterial soap additive, in the environment and in human beings. Indeed, the Food and Drug Administration has recently banned it from personal care products. Herein, we report the synthesis, antibacterial activity and cytotoxicity of novel

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsBiofilmsCarbanilidesCathetersHumansMicrobial Sensitivity TestsMolecular StructureMutation RateStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsAnti-Infective AgentsCarbanilidestriclocarbanantibacterialGram-positiveN,N′-diarylureaspentafluorosulfanylStaphylococcus aureustriclocarban

Identifiers

PMID30400165
PMCPMC6278391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.