Evidence map›Paper›PMID 30398975›Full record

ArticleAging2018

BK channel overexpression on plasma membrane of fibroblasts from Hutchinson-Gilford progeria syndrome.

Isabella Zironi, Entelë Gavoçi, Giovanna Lattanzi, Angela Virelli, Fabrizio Amorini, Daniel Remondini, Gastone Castellani

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The Role of KCNMB1 and BK Channels in Myofibroblast Differentiation and Pulmonary Fibrosis.American journal of respiratory cell and molecular biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Isabella ZironiDepartment of Physics and Astronomy (D.I.F.A.) University of Bologna, Bologna, Italy.
Entelë GavoçiNational Institute for Nuclear Physics (INFN), Bologna, Italy.
Giovanna LattanziCNR Institute of Molecular Genetics, Unit of Bologna, Bologna, Italy.
Angela VirelliDepartment of Physics and Astronomy (D.I.F.A.) University of Bologna, Bologna, Italy.
Fabrizio AmoriniDepartment of Physics and Astronomy (D.I.F.A.) University of Bologna, Bologna, Italy.
Daniel RemondiniDepartment of Physics and Astronomy (D.I.F.A.) University of Bologna, Bologna, Italy.
Gastone CastellaniDepartment of Physics and Astronomy (D.I.F.A.) University of Bologna, Bologna, Italy.
Istituto Nazionale di Fisica Nucleare, Sezione di Bologna · ITUniversity of Bologna · ITIstituto Ortopedico Rizzoli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare genetic disorder wherein symptoms resembling aspects of aging are manifested at a very early age. It is a genetic condition that occurs due to a

Indexed as

AdolescentAdultAgedAged, 80 and overCell AdhesionCell MembraneCell ProliferationChildFibroblastsGene Expression RegulationHumansLamin Type ALarge-Conductance Calcium-Activated Potassium ChannelsProgeriaYoung AdultLamin Type ALarge-Conductance Calcium-Activated Potassium ChannelsLMNA protein, humanagingcellular proliferationgene LMNAHutchinson-Gilford Progeria Syndrome (HGPS)K current +membrane channelspatch clamp

Identifiers

PMID30398975
PMCPMC6286842
OpenAlexW2899633155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.