Evidence map›Paper›PMID 30398470›Full record

ArticleScientific data2018

Enabling precision medicine in neonatology, an integrated repository for preterm birth research.

Marina Sirota, Cristel G Thomas, Rebecca Liu, Maya Zuhl, Payal Banerjee, Ronald J Wong, Cecele C Quaintance, Rita Leite, Jessica Chubiz, Rebecca Anderson and 12 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific data, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. VMAP: Vaginal Microbiome Atlas During Pregnancy.medRxiv : the preprint server for health sciences · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Understanding health disparities.Journal of perinatology : official journal of the California Perinatal Association · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 9 institutions in 1 country.

Marina SirotaInstitute for Computational Health Sciences, University of California, San Francisco, CA 94158, USA.
Cristel G ThomasNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.
Rebecca LiuEnterprise Science And Computing, Inc., Rockville, MD 20850, USA.
Maya ZuhlMarch of Dimes, White Plains, NY 10605, USA.
Payal BanerjeeMarch of Dimes, White Plains, NY 10605, USA.
Ronald J WongMarch of Dimes Prematurity Research Center at Stanford, Department of Pediatrics, Stanford University School of Medicine Stanford, CA 94305, USA.ORCID 0000-0003-1205-6936
Cecele C QuaintanceMarch of Dimes Prematurity Research Center at Stanford, Department of Pediatrics, Stanford University School of Medicine Stanford, CA 94305, USA.
Rita LeitePerelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Jessica ChubizDepartment of Obstetrics and Gynecology, Washington University in St Louis, St. Louis, MO 63110, USA.
Rebecca AndersonDepartment of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
Joanne ChappellCincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
Mara KimDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.
William GrobmanDepartment of Obstetrics and Gynecology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60637, USA.
Ge ZhangCincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
Antonis RokasDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.ORCID 0000-0002-7248-6551
Sarah K EnglandDepartment of Obstetrics and Gynecology, Washington University in St Louis, St. Louis, MO 63110, USA.
Samuel ParryPerelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.
Gary M ShawMarch of Dimes Prematurity Research Center at Stanford, Department of Pediatrics, Stanford University School of Medicine Stanford, CA 94305, USA.
Joe Leigh SimpsonEnterprise Science And Computing, Inc., Rockville, MD 20850, USA.
Elizabeth ThomsonNorthrop Grumman Health Solutions, Rockville, MD 20850, USA.ORCID 0000-0002-1267-6062
Atul J ButteInstitute for Computational Health Sciences, University of California, San Francisco, CA 94158, USA.ORCID 0000-0002-7433-2740
March of Dimes Prematurity Research Centers
March of Dimes · USCincinnati Children's Hospital Medical Center · USUniversity of Pennsylvania · USWashington University in St. Louis · USUniversity of Chicago · USNorthrop Grumman (United States) · USUniversity of California, San Francisco · USVanderbilt University · USNorthwestern University · US

Funding

Washington University Intellectual and Developmental Disabilities Research Center-Administrative Down Syndrome SupplementU54HD087011 · NICHD · WASHINGTON UNIVERSITY · PI CONSTANTINO, JOHN N. · 2015 to 2019
$7.1M
Maternal-Fetal Medicine Units Network -- The Northwestern Study CenterUG1HD040512 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Lynn M Yee · 2016 to 2026
$3.4M
Elucidating the Role of the Genetic and Environmental Determinants of Preterm Birth Using Integrative Computational ApproachesK01LM012381 · NLM · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SIROTA, MARINA · 2016 to 2018
$531k
NIAID NIH HHS HHSN272201200028CNICHD NIH HHS U54 HD087011NICHD NIH HHS UG1 HD040512NLM NIH HHS K01 LM012381
6 · The paper itself

Abstract

Preterm birth, or the delivery of an infant prior to 37 weeks of gestation, is a significant cause of infant morbidity and mortality. In the last decade, the advent and continued development of molecular profiling technologies has enabled researchers to generate vast amount of 'omics' data, which together with integrative computational approaches, can help refine the current knowledge about disease mechanisms, diagnostics, and therapeutics. Here we describe the March of Dimes' Database for Preterm Birth Research (http://www.immport.org/resources/mod), a unique resource that contains a variety of 'omics' datasets related to preterm birth. The database is open publicly, and as of January 2018, links 13 molecular studies with data across tens of thousands of patients from 6 measurement modalities. The data in the repository are highly diverse and include genomic, transcriptomic, immunological, and microbiome data. Relevant datasets are augmented with additional molecular characterizations of almost 25,000 biological samples from public databases. We believe our data-sharing efforts will lead to enhanced research collaborations and coordination accelerating the overall pace of discovery in preterm birth research.

Identifiers

PMID30398470
PMCPMC6219406
OpenAlexW2899896248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.