ArticleThe American journal of tropical medicine and hygiene2019
Depressive Symptoms Mediate the Associations of Stigma with Medication Adherence and Quality of Life in Tuberculosis Patients in China.
Article in The American journal of tropical medicine and hygiene, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Community-based, peer-led psychosocial support to address stigma and reduce depression among adults with tuberculosis in Indonesia: A prospective interventional cohort study.PLOS global public health · 2026Article
- Barriers to treatment adherence among patients with tuberculosis: a qualitative study of Pakistani nationals and Afghan refugees.BMJ open · 2025Article
- The Association Between Medication Adherence, Internalized Stigma and Social Support Among Outpatients with Major Depressive Disorder in a Malaysian Hospital: A Cross-Sectional Study.Psychology research and behavior management · 2025Article
- Stigma, depression, and quality of life among people with pulmonary tuberculosis diagnosed through active and passive case finding in Nepal: a prospective cohort study.BMC global and public health · 2024Article
- Stigma, depression, quality of life, and the need for psychosocial support among people with tuberculosis in Indonesia: A multi-site cross-sectional study.PLOS global public health · 2024Article
- Effects of Social Support on Medication Adherence Among Patients with Schizophrenia: Serial Multiple Mediation Model.Patient preference and adherence · 2024Article
- The relationship between stigma and quality of life in hospitalized middle-aged and elderly patients with chronic diseases: the mediating role of depression and the moderating role of psychological resilience.Frontiers in psychiatry · 2024Article
- Living with tuberculosis: a qualitative study of patients' experiences with disease and treatment.BMC public health · 2022Article
- Internalized and Perceived Stigma and Depression in Pulmonary Tuberculosis: Do They Explain the Relationship Between Drug Sensitivity Status and Adherence?Frontiers in psychiatry · 2022Article
- The relationship among social support, experienced stigma, psychological distress, and quality of life among tuberculosis patients in China.Scientific reports · 2021Article
- Identifying contextual determinants of problems in tuberculosis care provision in South Africa: a theory-generating case study.Infectious diseases of poverty · 2021Article
- Health related quality of life and associated factors with medication adherence among tuberculosis patients in selected districts of Gandaki Province of Nepal.Journal of clinical tuberculosis and other mycobacterial diseases · 2021Article
- Tuberculosis-related stigma and its determinants in Dalian, Northeast China: a cross-sectional study.BMC public health · 2021Article
- Social stigma among tuberculosis patients attending DOTS centers in Delhi.Journal of family medicine and primary care · 2020Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stigma has been associated with health-related outcomes such as medication adherence and quality of life (QOL) in patients with tuberculosis (TB); however, the mechanisms via which TB-related stigma interferes with specific outcomes are unclear. This study aimed to determine whether depressive symptoms were one of the mechanisms that mediated the associations between TB-related stigma and both medication adherence and QOL in patients with TB. A cross-sectional survey was conducted between October 1, 2013, and March 31, 2014, in Hubei Province, central China, and data were collected from 1,342 patients with TB, using a structured questionnaire that measured TB-related stigma, depressive symptoms, medication adherence, and QOL. Multiple imputation was used to account for missing data. Structural equation modeling was performed to assess the mediating effect of depressive symptoms on the associations of TB-related stigma with medication adherence and QOL. Mediation analyses showed that depressive symptoms partially mediated the association between TB-related stigma and medication adherence (standardized indirect effect = -0.16, 95% bias-corrected confidence interval [CI] [-0.19, -0.13],
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