Evidence map›Paper›PMID 30397864›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020

Utility of nuclear stress imaging in predicting long-term outcomes one-year post CABG Surgery.

Fernando Ortiz, Mackenzi Mbai, Selcuk Adabag, Santiago Garcia, Jennifer Nguyen, Steven Goldman, Herbert B Ward, Rosemary F Kelly, Selma Carlson, William L Holman and 1 more

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Indicators of abnormal PET coronary flow capacity in detecting cardiac ischemia.The international journal of cardiovascular imaging · 2023
    Article
  2. Clinical implications of compromisedJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Fernando OrtizUniversity of Minnesota, Minneapolis, MN, USA. ortiz091@umn.edu.
Mackenzi MbaiVA Medical Center Minneapolis, University of Minnesota, Minneapolis, MN, USA.
Selcuk AdabagVA Medical Center Minneapolis, University of Minnesota, Minneapolis, MN, USA.
Santiago GarciaVA Medical Center Minneapolis, University of Minnesota, Minneapolis, MN, USA.
Jennifer NguyenVA Medical Center Minneapolis, Minneapolis, MN, USA.
Steven GoldmanSouthern Arizona VA Health Systems, University of Arizona, Tucson, AZ, USA.
Herbert B WardVA Medical Center Minneapolis, University of Minnesota, Minneapolis, MN, USA.
Rosemary F KellyVA Medical Center Minneapolis, University of Minnesota, Minneapolis, MN, USA.
Selma CarlsonVA Medical Center Minneapolis, Minneapolis, MN, USA.
William L HolmanBirmingham VA Medical Center, University of Alabama Birmingham, Birmingham, AL, USA.
Edward O McFallsVA Medical Center Minneapolis, University of Minnesota, Minneapolis, MN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly MPI after CABG is currently considered rarely appropriate in asymptomatic patients. This study aimed to identify prognostic value of nuclear stress-imaging post-CABG.

methodsThis was a single center prospective study looking at long-term outcomes post-CABG. Per protocol participants underwent SPECT-MPI stress testing and coronary angiogram on the same day, 1-year following CABG. Defect size was semi-quantified. The primary outcomes were the composite of death and congestive heart failure.

resultsEighty-four participants underwent nuclear stress-imaging and angiography, with a median follow-up of 11.1 years. Three separate stress findings predicted the primary outcome: inability to reach stage 3 of a Bruce protocol (OR 7.3, CI 2.4-22.1, P < 0.001), LVEF < 45% (OR 4.0, CI 1.1-15.3, P = 0.041) and a moderate-large stress defect size (HR 2.31, CI 1.1-1.5, P = 0.04). These findings appear to be additive and strongest among patients who underwent exercise stress testing (HR 10.6, CI 3.6-30.6, P < 0.001). Graft disease was identified in 39 (46%) patients and compared to those individuals with no graft disease, did not predict long-term adverse outcomes (P = 0.29).

conclusionIn clinically stable patients early after revascularization with CABG, SPECT-MPI can identify patients at higher risk of heart failure and death.

Indexed as

AgedCoronary AngiographyCoronary Artery BypassCoronary Artery DiseaseExercise TestFemaleHeart FailureHumansKaplan-Meier EstimateMagnetic Resonance ImagingMaleMiddle AgedMultimodal ImagingMyocardial Perfusion ImagingMyocardial RevascularizationPrognosisCADExercise testingHeart failureMPIOutcomes researchSPECT

Identifiers

PMID30397864

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.