Evidence map›Paper›PMID 30397817›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2019

Prepulse modulation and recovery of trigemino-cervical reflex in normal subjects.

Meral E Kızıltan, Pınar Bekdik Şirinocak, Tuba Akıncı, Tuba Cerrahoğlu Şirin, Burcu Nuran Arkalı, Fatma Candan, Ayşegül Gündüz

Abstract read
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Central nervous system physiology.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meral E KızıltanDepartment of Neurology, Cerrahpaşa School of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Turkey.
Pınar Bekdik ŞirinocakDepartment of Neurology, Kocaeli Derince Education and Research Hospital, Istanbul, Turkey.
Tuba AkıncıDepartment of Neurology, Beylikdüzü State Hospital, Istanbul, Turkey.
Tuba Cerrahoğlu ŞirinDepartment of Neurology, Sisli Hamidiye Etfal Education and Research Hospital, Istanbul, Turkey.
Burcu Nuran ArkalıDepartment of Neurology, Cerrahpaşa School of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Turkey.
Fatma CandanDepartment of Neurology, Goztepe Education and Research Hospital, Istanbul Medeniyet University, Istanbul, Turkey.
Ayşegül GündüzDepartment of Neurology, Cerrahpaşa School of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Turkey. draysegulgunduz@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn this study, we analyzed the inhibitory control on the trigemino-cervical reflex (TCR), and whether or not prepulse modulation (PPM) has an effect on TCR. Thus, we studied the PPM of TCR. We hypothesized that TCR would presumably be under the modulatory effect after the prepulse stimulus similar to blink reflex (BR). We also studied the recovery of TCR which was previously shown.

methodsWe included 13 healthy individuals. All subjects underwent recordings of TCR, TCR-PPM, and recovery of TCR. For TCR-PPM, a subthreshold stimulus to second finger 50 or 100 ms before the test stimulus was applied. For recovery of TCR, two stimuli at the infraorbital nerve were applied at 300, 500, and 800 ms interstimulus intervals (ISIs).

resultsThere was an inhibition of bilateral late responses of TCR at the ISIs of both 50 ms and 100 ms. There was no change of latencies. Full recovery of TCR did not develop even at the ISI 800 ms. DISCUSSION: We have provided an evidence for the TCR-PPM in healthy subjects for the first time in this study. The prepulse inhibition is attributed to the functions of the pedunculopontine tegmental nucleus. Our study provides a strong indication that there are connections between pedunculopontine tegmental nucleus and trigemino-cervical circuit, which produces TCR.

Indexed as

Head MovementsPrepulse InhibitionReflexAdultElectric StimulationFaceFemaleFingersHumansMaleMiddle AgedPedunculopontine Tegmental NucleusTime FactorsPedunculopontine tegmental nucleusPrepulse inhibition (PPI)Prepulse modulation (PPM)RecoveryTrigemino-cervical reflex (TCR)

Identifiers

PMID30397817

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.