Evidence map›Paper›PMID 30397431›Full record

ReviewJournal of tissue engineering

Auditory disorders and future therapies with delivery systems.

Jung-Hwan Lee, Min Young Lee, Yohan Lim, Jonathan Knowles, Hae-Won Kim

Abstract readReview
In one paragraph

Review in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Alginate scaffolds improve functional recovery after spinal cord injury.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Pooled it
  2. Rational Design of Inner Ear Drug Delivery Systems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. Roles of Sirtuins in Hearing Protection.Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Effect of Angiogenesis in Bone Tissue Engineering.Annals of biomedical engineering · 2022
    Review
  6. Review
  7. The Use of Nanoparticles in Otoprotection.Frontiers in neurology · 2022
    Review
  8. Article
  9. Article
  10. Inner Ear Gene Delivery: Vectors and Routes.Hearing, balance and communication · 2020
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jung-Hwan LeeInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea.
Min Young LeeBeckman Laser Institute Korea, College of Medicine, Dankook University, Cheonan, Republic of Korea.
Yohan LimInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea.
Jonathan KnowlesUCL Eastman - Korea Dental Medicine Innovation Center, Dankook University, Cheonan, Republic of Korea.
Hae-Won KimInstitute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Auditory function takes a major part in human life. While sensorineural hearing loss is related with many factors including genetic disorders, age and noise, the clear causes are not well understood. Even more, the currently available treatments with drugs cause side effects, which thus are considered suboptimal. Here, we communicate the delivery systems with biomaterials that can be possible therapeutic options to restore hearing and vestibular functions. We introduce briefly the various pathological factors related with hearing loss and the limitation of current therapies, detail the recent studies on delivery systems including nanoparticles and hydrogels and discuss future clinical availability.

Indexed as

clinical availabilityHearing losshydrogelinner ear deliverynanoparticle

Identifiers

PMID30397431
PMCPMC6207966

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.