ArticleScientific reports2018
Relationship between cardiovascular health metrics and physical performance in community-living people: Results from the Longevity check-up (Lookup) 7+ project.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 31 citations in OpenAlex.
- The Combined Effect of Multisensory Stimulation and Therapist Support on Physical and Mental Health of Older Adults Living in Nursing Homes: Pilot Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
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- Associations between sarcopenia operationalized using muscle strength or power and health-related parameters.The Journal of frailty & aging · 2025Article
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- Cross-sectional associations between dietary intake of polyunsaturated fatty acids, physical function, and sarcopenia in community-dwelling older adults.The journal of nutrition, health & aging · 2025Article
- Common Physical Performance Tests for Evaluating Health in Older Adults: Cross-Sectional Study.Interactive journal of medical research · 2024Article
- Waist-to-calf circumference ratio as a potential indicator of diabetes risk: results from the Longevity Check-Up (Lookup) 8.Scientific reports · 2024Article
- Article
- Adherence to aerobic training combined with high protein intake is associated with low blood pressure in Italian older adults: a cross-sectional study.Aging clinical and experimental research · 2023Article
- Combined Aerobic Training and Mediterranean Diet Is Not Associated with a Lower Prevalence of Sarcopenia in Italian Older Adults.Nutrients · 2023Article
- Engagement in Aerobic Exercise Is Associated with a Reduced Prevalence of Sarcopenia and Severe Sarcopenia in Italian Older Adults.Journal of personalized medicine · 2023Article
- Protein Intake Is Associated with Blood Pressure and Cholesterol Levels in Italian Older Adults: A Cross-Sectional Study.Metabolites · 2023Article
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- Article
- Sarcopenia as potential biological substrate of long COVID-19 syndrome: prevalence, clinical features, and risk factors.Journal of cachexia, sarcopenia and muscle · 2022Article
- Prevalence of dyslipidemia and hypercholesterolemia awareness: results from the Lookup 7+ online project.European journal of public health · 2022Article
- Health-related quality of life after first-ever acute ischemic stroke: associations with cardiovascular health metrics.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- MADRID+90 study on factors associated with longevity: Study design and preliminary data.PloS one · 2021Article
- Association between Dietary Habits and Physical Function in Brazilian and Italian Older Women.Nutrients · 2020Article
- Relationship between pulmonary function and physical performance among community-living people: results from Look-up 7+ study.Journal of cachexia, sarcopenia and muscle · 2020Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cardiovascular health metrics (CHMs) may predict disability independent of vascular events. Though, the link between CHMs and physical performance is unclear. This relationship was explored using data from the Longevity check-up (Lookup) 7+ project. Lookup 7+ is an ongoing cross-sectional survey conducted in unconventional settings across Italy. People who are at least 18-year-old and provide written informed consent are eligible. CHMs [i.e., smoking status, healthy diet, body mass index (BMI), blood pressure, blood cholesterol, and diabetes status] are assessed through closed questions and objective measurements. Physical performance is measured via the 5-repetition chair-stand test. Analyses included 7446 participants (55.5 ± 14.9 years; 56% women). Physical performance positively correlated with CHMs scores, such that participants who scored higher (6-7 points) completed the chair-stand test about 2 s faster than those scoring lower (1-2 points). In fully adjusted analysis, better physical performance was more frequently observed in younger, non-smoking, physically active men, with ideal BMI, and no diabetes. Our findings indicate a gradient of better physical function with increasing CHMs scores. Future investigations should establish the longitudinal effect of unhealthy behaviours and cardiovascular risk factors on physical performance and verify whether implementation of large-scale primordial cardiovascular prevention may positively impact physical fitness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.