Evidence map›Paper›PMID 30397340›Full record

ArticleNature microbiology2018

A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.

Jonathan N Pruneda, Robert J Bastidas, Erithelgi Bertsoulaki, Kirby N Swatek, Balaji Santhanam, Michael J Clague, Raphael H Valdivia, Sylvie Urbé, David Komander

Open access · greenAbstract read
In one paragraph

Article in Nature microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Pathogen-induced rerouting of host membrane trafficking.Current opinion in cell biology · 2025
    Review
  10. Article
  11. Review
  12. mBio · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. TheMicrobiology spectrum · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Jonathan N PrunedaDivision of Protein and Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK.
Robert J BastidasDepartment of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.
Erithelgi BertsoulakiCellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
Kirby N SwatekDivision of Protein and Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK.
Balaji SanthanamDivision of Structural Studies, MRC Laboratory of Molecular Biology, Cambridge, UK.
Michael J ClagueCellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0003-3355-9479
Raphael H ValdiviaDepartment of Molecular Genetics and Microbiology, Duke University, Durham, NC, USA.ORCID http://orcid.org/0000-0003-0961-073X
Sylvie UrbéCellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
David KomanderDivision of Protein and Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Cambridge, UK. dk@mrc-lmb.cam.ac.uk.ORCID http://orcid.org/0000-0002-8092-4320
MRC Laboratory of Molecular Biology · GBUniversity of Liverpool · GBDuke University · US

Funding

Serologic Biomarkers of Human Sexually Transmitted Infection and DiseaseU19AI084044 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BAVOIL, PATRIK M, RAVEL, JACQUES · 2009 to 2018
$22.8M
Forward and Reverse Genetics in ChlamydiaR01AI100759 · NIAID · DUKE UNIVERSITY · PI VALDIVIA, RAPHAEL H · 2012 to 2016
$2.2M
Data commons for 'omic, microscopy and analysis core facilitiesS10OD018164 · OD · DUKE UNIVERSITY · PI WRAY, GREGORY A. · 2014 to 2014
$598k
Medical Research Council MC_U105192732NIAID NIH HHS R01 AI100759NIAID NIH HHS U19 AI084044NIH HHS S10 OD018164
6 · The paper itself

Abstract

Pathogenic bacteria are armed with potent effector proteins that subvert host signalling processes during infection

Indexed as

Protein Processing, Post-TranslationalA549 CellsAcetylationAcetyltransferasesAnimalsBacterial ProteinsChlamydia InfectionsChlamydia trachomatisChlorocebus aethiopsDeubiquitinating EnzymesGene Expression Regulation, BacterialGolgi ApparatusHeLa CellsHumansModels, MolecularMutationAcetyltransferasesBacterial ProteinsDeubiquitinating Enzymes

Identifiers

PMID30397340
PMCPMC6319605
OpenAlexW2898232581

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.