Evidence map›Paper›PMID 30397173›Full record

ArticleThe Journal of experimental biology2019

Deletion of a specific exon in the voltage-gated calcium channel gene

Kayly M Lembke, Alexander D Law, Jasmine Ahrar, David B Morton

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of experimental biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Invertebrate genetic models of amyotrophic lateral sclerosis.Frontiers in molecular neuroscience · 2024
    Review
  3. Physiologic and Nanoscale Distinctions Define Glutamatergic Synapses in Tonic vs Phasic Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  4. Amyotrophic Lateral Sclerosis Genes inInternational journal of molecular sciences · 2021
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kayly M LembkeProgram in Molecular and Cellular Biosciences, Department of Physiology and Pharmacology, Oregon Health & Science University, Portland, OR 97239, USA.
Alexander D LawDepartment of Integrative Biosciences, Oregon Health & Science University, Portland, OR 97239, USA.ORCID 0000-0002-0954-7147
Jasmine AhrarDepartment of Integrative Biosciences, Oregon Health & Science University, Portland, OR 97239, USA.
David B MortonDepartment of Integrative Biosciences, Oregon Health & Science University, Portland, OR 97239, USA mortonda@ohsu.edu.ORCID 0000-0002-1320-653X
Oregon Health & Science University · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Using Drosophila as a model to understand TDP-43 function in ALSR21NS071186 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI MORTON, DAVID B · 2011 to 2012
$410k
NIH HHS P40 OD018537NINDS NIH HHS R21 NS071186
6 · The paper itself

Abstract

TAR DNA-binding protein 43 (TDP-43) is an RNA-binding protein that regulates transcription, translation and alternative splicing of mRNA. We have shown previously that null mutations of the

Indexed as

Sequence DeletionAnimalsBase SequenceCalcium ChannelsDrosophila melanogasterDrosophila ProteinsExonsLarvaLocomotioncac protein, DrosophilaCalcium ChannelsDrosophila ProteinsALSDmca1AModel organismMotor programNeurodegenerationTDP-43

Identifiers

PMID30397173
PMCPMC6340135
OpenAlexW2900015431

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.