Evidence map›Paper›PMID 30397071›Full record

ArticleAntimicrobial agents and chemotherapy2019

Inducible Cell Fusion Permits Use of Competitive Fitness Profiling in the Human Pathogenic Fungus Aspergillus fumigatus.

Darel Macdonald, Darren D Thomson, Anna Johns, Adriana Contreras Valenzuela, Jane M Gilsenan, Kathryn M Lord, Paul Bowyer, David W Denning, Nick D Read, Michael J Bromley

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Fungal Pathogens: Shape-Shifting Invaders.Trends in microbiology · 2020
    Review
  12. Parasexual recombination enablesERJ open research · 2020
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. High-Throughput Gene Replacement in Aspergillus fumigatus.Current protocols in microbiology · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Darel Macdonald *Manchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.
Darren D Thomson *Manchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.
Anna Johns *Manchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.
Adriana Contreras ValenzuelaManchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.
Jane M GilsenanManchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.
Kathryn M LordFungal Cell Biology Group, Institute of Cell Biology, The University of Edinburgh, Edinburgh, United Kingdom.
Paul BowyerManchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.
David W DenningManchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom.
Nick D ReadManchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom nick.read@manchester.ac.uk mike.bromley@manchester.ac.uk.
Michael J BromleyManchester Fungal Infection Group, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom nick.read@manchester.ac.uk mike.bromley@manchester.ac.uk.
University of Manchester · GBManchester Academic Health Science Centre · GBUniversity of Edinburgh · GB

Funding

Wellcome TrustWellcome Trust 208396/Z/17/Z
6 · The paper itself

Abstract

Antifungal agents directed against novel therapeutic targets are required for treating invasive, chronic, and allergic

Indexed as

ADP-Ribosylation FactorsAntifungal AgentsAspergillosisAspergillus fumigatusBrefeldin ACell FusionCytochrome P-450 Enzyme SystemDrug Resistance, Multiple, FungalFungal ProteinsGene Knockout TechniquesHumansItraconazoleMicrobial Sensitivity TestsMitochondrial Proton-Translocating ATPasesADP-Ribosylation FactorsAntifungal AgentsBrefeldin Acytochrome P-450 CYP51A, AspergillusCytochrome P-450 Enzyme SystemFungal ProteinsItraconazoleMitochondrial Proton-Translocating ATPasesanastomosisantifungalAspergillus fumigatuschemical genomicsfunctional genomicshyphal fusionimaging

Identifiers

PMID30397071
PMCPMC6325235
OpenAlexW2900139271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.