Evidence map›Paper›PMID 30397021›Full record

ArticlePlant physiology2019

Identification and Microbial Production of the Raspberry Phenol Salidroside that Is Active against Huntington's Disease.

Nicolai Kallscheuer, Regina Menezes, Alexandre Foito, Marcelo Henriques da Silva, Adelaide Braga, Wijbrand Dekker, David Méndez Sevillano, Rita Rosado-Ramos, Carolina Jardim, Joana Oliveira and 12 more

Open access · greenAbstract read
In one paragraph

Article in Plant physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Efficient production of hydroxysalidroside inSynthetic and systems biotechnology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 5 countries.

Nicolai KallscheuerInstitut für Bio- und Geowissenschaften (IBG-1: Biotechnologie), Forschungszentrum Jülich, Jülich 52428, Germany.ORCID 0000-0003-4925-6923
Regina MenezesInstituto de Biologia Experimental e Tecnológica (iBET), 2781-901 Oeiras, Portugal.ORCID 0000-0003-0552-8480
Alexandre FoitoThe James Hutton Institute, Invergowrie, DD2 5DA Dundee, Scotland, United Kingdom.ORCID 0000-0001-6111-5256
Marcelo Henriques da SilvaDepartment of Biotechnology, Delft University of Technology, 2629 HZ Delft, The Netherlands.ORCID 0000-0002-8606-5598
Adelaide BragaBiotempo, 4805-017 Guimarães, Portugal.ORCID 0000-0001-7432-0726
Wijbrand DekkerEvolva, 4053 Reinach, Switzerland.
David Méndez SevillanoDepartment of Biotechnology, Delft University of Technology, 2629 HZ Delft, The Netherlands.ORCID 0000-0003-0643-6705
Rita Rosado-RamosInstituto de Biologia Experimental e Tecnológica (iBET), 2781-901 Oeiras, Portugal.ORCID 0000-0002-1294-9227
Carolina JardimInstituto de Biologia Experimental e Tecnológica (iBET), 2781-901 Oeiras, Portugal.ORCID 0000-0001-6929-6469
Joana OliveiraBiotempo, 4805-017 Guimarães, Portugal.
Patrícia FerreiraBiotempo, 4805-017 Guimarães, Portugal.
Isabel RochaBiotempo, 4805-017 Guimarães, Portugal.ORCID 0000-0001-9494-3410
Ana Rita SilvaBiotempo, 4805-017 Guimarães, Portugal.
Márcio SousaBiotempo, 4805-017 Guimarães, Portugal.
J William AllwoodThe James Hutton Institute, Invergowrie, DD2 5DA Dundee, Scotland, United Kingdom.ORCID 0000-0001-6433-2694
Michael BottInstitut für Bio- und Geowissenschaften (IBG-1: Biotechnologie), Forschungszentrum Jülich, Jülich 52428, Germany.ORCID 0000-0002-4701-8254
Nuno FariaBiotempo, 4805-017 Guimarães, Portugal.ORCID 0000-0001-5271-8178
Derek StewartThe James Hutton Institute, Invergowrie, DD2 5DA Dundee, Scotland, United Kingdom.ORCID 0000-0001-9838-4265
Marcel OttensDepartment of Biotechnology, Delft University of Technology, 2629 HZ Delft, The Netherlands.
Michael NaesbyEvolva, 4053 Reinach, Switzerland.ORCID 0000-0001-9422-3077
Cláudia Nunes Dos SantosInstituto de Biologia Experimental e Tecnológica (iBET), 2781-901 Oeiras, Portugal j.marienhagen@fz-juelich.de.ORCID 0000-0002-5809-1924
Jan MarienhagenInstitut für Bio- und Geowissenschaften (IBG-1: Biotechnologie), Forschungszentrum Jülich, Jülich 52428, Germany j.marienhagen@fz-juelich.de.ORCID 0000-0001-5513-3730
Stemmatters (Portugal) · PTInstituto de Biologia Experimental e Tecnológica · PTDelft University of Technology · NLForschungszentrum Jülich · DEJames Hutton Institute · GBEvolva (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Edible berries are considered to be among nature's treasure chests as they contain a large number of (poly)phenols with potentially health-promoting properties. However, as berries contain complex (poly)phenol mixtures, it is challenging to associate any interesting pharmacological activity with a single compound. Thus, identification of pharmacologically interesting phenols requires systematic analyses of berry extracts. Here, raspberry (

Indexed as

Biosynthetic PathwaysChemical FractionationGlucosidesHuntingtin ProteinHuntington DiseaseModels, BiologicalPhenolsPlant ExtractsRubusSaccharomyces cerevisiaeGlucosidesHuntingtin ProteinPhenolsPlant Extractsrhodioloside

Identifiers

PMID30397021
PMCPMC6393794
OpenAlexW2899932396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.