Evidence map›Paper›PMID 30397005›Full record

ArticleMolecular systems biology2018

Synthesis and degradation of FtsZ quantitatively predict the first cell division in starved bacteria.

Karthik Sekar, Roberto Rusconi, John T Sauls, Tobias Fuhrer, Elad Noor, Jen Nguyen, Vicente I Fernandez, Marieke F Buffing, Michael Berney, Suckjoon Jun and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecular systems biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 67 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Building the Bacterial Divisome at the Septum.Sub-cellular biochemistry · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
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  16. β-Oxidation and autophagy are critical energy providers during acute glucose depletion in SProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Karthik SekarDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.ORCID 0000-0003-2045-9364
Roberto RusconiDepartment of Civil, Environmental and Geomatic Engineering, Institute of Environmental Engineering, ETH Zurich, Zurich, Switzerland.
John T SaulsDepartment of Physics, University of California at San Diego, La Jolla, CA, USA.
Tobias FuhrerDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.ORCID 0000-0001-5006-6874
Elad NoorDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Jen NguyenDepartment of Civil, Environmental and Geomatic Engineering, Institute of Environmental Engineering, ETH Zurich, Zurich, Switzerland.
Vicente I FernandezDepartment of Civil, Environmental and Geomatic Engineering, Institute of Environmental Engineering, ETH Zurich, Zurich, Switzerland.
Marieke F BuffingDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland.
Michael BerneyDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA.
Suckjoon JunDepartment of Physics, University of California at San Diego, La Jolla, CA, USA.ORCID 0000-0002-0139-4297
Roman StockerDepartment of Civil, Environmental and Geomatic Engineering, Institute of Environmental Engineering, ETH Zurich, Zurich, Switzerland.
Uwe SauerDepartment of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, Switzerland sauer@imsb.biol.ethz.ch.ORCID 0000-0002-5923-0770
ETH Zurich · CHUniversity of California San Diego · USAlbert Einstein College of Medicine · USHumanitas University · IT

Funding

R01 Supplement for Undergraduate Summer Research 2020R01GM118565 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JUN, SUCKJOON · 2016 to 2020
$1.7M
NIGMS NIH HHS R01 GM118565
6 · The paper itself

Abstract

In natural environments, microbes are typically non-dividing and gauge when nutrients permit division. Current models are phenomenological and specific to nutrient-rich, exponentially growing cells, thus cannot predict the first division under limiting nutrient availability. To assess this regime, we supplied starving

Indexed as

Bacterial ProteinsCell DivisionCytoskeletal ProteinsEscherichia coliGlucoseMetabolomicsMicrofluidic Analytical TechniquesProteolysisSingle-Cell AnalysisBacterial ProteinsCytoskeletal ProteinsFtsZ protein, BacteriaGlucosedivisionEscherichia coliFtsZprotein degradationstarvation

Identifiers

PMID30397005
PMCPMC6217170
OpenAlexW2900424448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.