ReviewThe Korean journal of internal medicine2018
Clinical implications of anti-thyroglobulin antibody measurement before surgery in thyroid cancer.
Review in The Korean journal of internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Diagnostic performance of 2-[Endocrine · 2025Pooled it
- Thyroglobulin Autoantibodies Do Not Influence the Outcome of Patients With Differentiated Thyroid Carcinoma.Endocrinology, diabetes & metabolism · 2026Article
- Preoperative anti-thyroid antibodies predict malignancy risk in cytologically indeterminate thyroid nodules: a prospective multicenter study.Gland surgery · 2025Article
- National recommendations of the Croatian society of medical biochemistry and laboratory medicine: Thyroid function tests from the laboratory point of view.Biochemia medica · 2025Review
- New insights into the phenomenon of remissions and relapses in autoimmune diseases and the puzzle of benign autoantibodies in healthy individuals.Frontiers in immunology · 2025Review
- Thyroid cancer survival and prognostic factors in Yantai, China (2012-2022): a population-based study.BMC cancer · 2024Article
- Article
- Thyroid auto-antibodies in newly diagnosed multiple sclerosis patients: A cross sectional study.Health science reports · 2024Article
- Application of thyroglobulin and anti-thyroglobulin antibody combined with emission computed tomography in the adjuvant diagnosis of differentiated thyroid carcinoma.Annals of medicine · 2023Article
- Cervical lymph node metastasis prediction of postoperative papillary thyroid carcinoma beforeFrontiers in endocrinology · 2023Article
- Increased prevalence of autoimmune thyroid disease after COVID-19: A single-center, prospective study.Frontiers in endocrinology · 2023Article
- Clinical Value of Ultrasonography and Serum Markers in Preoperative N Staging of Thyroid Cancer.Cells · 2022Article
- Factors affecting recurrence in subacute granulomatous thyroiditis.Archives of endocrinology and metabolism · 2022Article
- Transcriptomic Analysis of Papillary Thyroid Cancer: A Focus on Immune-Subtyping, Oncogenic Fusion, and Recurrence.Clinical and experimental otorhinolaryngology · 2022Article
- Changing Paradigm in Treatment of Differentiated Thyroid Cancer.Indian journal of surgical oncology · 2022Review
- Lymph node metastasis of papillary thyroid carcinoma in the context of Hashimoto's thyroiditis.BMC endocrine disorders · 2022Article
- Relationship Between Thyroid Autoantibodies and Recurrence of Papillary Thyroid Carcinoma in Children and Adolescents.Frontiers in oncology · 2022Article
- Prognostic Value of Serum Thyroglobulin and Anti-Thyroglobulin Antibody in Thyroid Carcinoma Patients following Thyroidectomy.Diagnostics (Basel, Switzerland) · 2021Article
- Exosomal miR-130a-3p promotes the progression of differentiated thyroid cancer by targeting insulin-like growth factor 1.Oncology letters · 2021Article
- Significance of Anti-TPO as an Early Predictive Marker in Thyroid Disease.Autoimmune diseases · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thyroglobulin antibody (TgAb) is a class G immunoglobulin and a conventional marker for thyroid autoimmunity. From a clinical perspective, TgAb is less useful than thyroid peroxidase antibodies for predicting thyroid dysfunction. However, TgAb is found more frequently in differentiated thyroid cancer (DTC) and can interfere with thyroglobulin (Tg) measurements, which are used to monitor the recurrence or persistence of DTC. Recent studies suggested a small but consistent role for preoperative TgAb in predicting DTC in thyroid nodules, and in reflecting adverse tumor characteristics or prognosis, including lymph node metastasis, but this is still controversial. Postoperative TgAb can serve as a biomarker for remnant thyroid tissue, so follow-up measures of TgAb are useful for predicting cancer recurrence in DTC patients. Since high serum TgAb levels may also affect the fine needle aspiration washout Tg levels from suspicious lymph nodes of DTC patients, it is important to use caution when interpreting the washout Tg levels in patients who are positive for TgAb.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.