Evidence map›Paper›PMID 30396181›Full record

Trial reportMedical principles and practice : international journal of the Kuwait University, Health Science Centre2019

Does Tourniquet Time or Pressure Contribute to Intracranial Pressure Increase following Tourniquet Application?

Ahmet Besir, Ersagun Tugcugil

Registry-linked trialOpen access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04710225 (Does Anesthetic Technique Affect Pneumatic Tourniquet Pressures in Upper Limb Fracture Surgery? A Comparison of General Anesthesia and Axillary Brachial Plexus Block), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04710225 nacompletednot on this map

Does Anesthetic Technique Affect Pneumatic Tourniquet Pressures in Upper Limb Fracture Surgery? A Comparison of General Anesthesia and Axillary Brachial Plexus Block

TypeinterventionalSponsorBaskent University Ankara HospitalRan2019 to 2021Enrolled69ConditionsInitial Systolic Blood Pressure (mmHg), Arterial Occlusion Pressure (mmHg), Tourniquet Time (Minutes), Quality of Bloodless Surgical Field (4 Point Scale)ArmsUpper limb fracture surgery and arterial occlusion pressure (AOP) estimation based tourniquet pressure (TP) setting
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Observational
  2. Article
  3. Observational
  4. The Utility of Ocular Ultrasonography to Evaluate the Influence of Tourniquet Application on Intracranial Pressure.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019
    Article
  5. Reply to the Comment Entitled "The Utility of Ocular Ultrasonography to Evaluate the Influence of Tourniquet Application on Intracranial Pressure".Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ahmet BesirDepartment of Anesthesiology and Critical Care, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey, ahmetbesir61@gmail.com.
Ersagun TugcugilDepartment of Anesthesiology and Critical Care, Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey.
Karadeniz Technical University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to determine whether an early increase in intracranial pressure (ICP) following the deflation of a tourniquet is related to the tourniquet time (TT) or tourniquet pressure (TP) and to identify a safe cut-off value for TT or TP. MATERIALS AND

methodsPatients who underwent elective orthopedic lower-extremity surgery under general anesthesia were randomized into 2 groups: group A (inflation with a pneumatic TP of systolic blood pressure + 100 mm Hg; n = 30) and group B (inflation using the arterial occlusion pressure formula; n = 30). The initial and maximum TPs, TT, and sonographic measurements of optic-nerve sheath diameter (ONSD) and end-tidal CO2 values were taken at specific time points (15 min before the induction of anesthesia, just before, and 5, 10, and 15 min after the tourniquet was deflated).

resultsThe initial and maximum TPs were found to be significantly higher in group A than in group B. At 5 min after the tourniquet deflation, there was a significant positive correlation between TT and ONSD (r = 0.57, p = 0.0001). When ONSD ≥5 mm was taken as a standard criterion, the safe cut-off value for the optimal TT was found to be < 67.5 min (sensitivity 87% and specificity 59.5%).

conclusionThe ICP increase in the early period after tourniquet deflation was well correlated with TT but not with TP. TT of ≥67.5 min was found to be the cut-off value and is considered the starting point of the increase in ICP after tourniquet deflation.

Indexed as

AdultAgedFemaleHumansIntracranial HypertensionIntracranial PressureMaleMiddle AgedOrthopedic ProceduresROC CurveTime FactorsTourniquetsTurkeyYoung AdultArterial occlusion pressureIntracranial pressureOptic nerve sheath diameterTourniquet

Identifiers

PMID30396181
PMCPMC6558323
OpenAlexW2900197868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.