Evidence map›Paper›PMID 30396114›Full record

ArticleBioorganic chemistry2019

Synthesis and DNA binding profile of monomeric, dimeric, and trimeric derivatives of crystal violet.

Omar Nuñez, Bianca Chavez, Ryan Shaktah, Paola Pereda Garcia, Thomas Minehan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioorganic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Omar NuñezDepartment of Chemistry and Biochemistry, California State University, Northridge, 18111 Nordhoff Street, Northridge, CA 91330, USA.
Bianca ChavezDepartment of Chemistry and Biochemistry, California State University, Northridge, 18111 Nordhoff Street, Northridge, CA 91330, USA.
Ryan ShaktahDepartment of Chemistry and Biochemistry, California State University, Northridge, 18111 Nordhoff Street, Northridge, CA 91330, USA.
Paola Pereda GarciaDepartment of Chemistry and Biochemistry, California State University, Northridge, 18111 Nordhoff Street, Northridge, CA 91330, USA.
Thomas MinehanDepartment of Chemistry and Biochemistry, California State University, Northridge, 18111 Nordhoff Street, Northridge, CA 91330, USA. Electronic address: thomas.minehan@csun.edu.
California State University, Northridge · US

Funding

MINORITY UNDERGRADUATE RESEARCH TRAININGT34GM008395 · NIGMS · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI ZAVALA, MARIAELENA B · 1990 to 2020
$9.7M
Synthesis and DNA binding affinity evaluation of novel gilvocarcin-C-glucosidesSC3GM096899 · NIGMS · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI MINEHAN, THOMAS GERARD · 2011 to 2014
$431k
NIGMS NIH HHS SC3 GM096899NIGMS NIH HHS T34 GM008395
6 · The paper itself

Abstract

Monomeric, dimeric, and trimeric derivatives of the triphenylmethane dye crystal violet (1a-1f) have been synthesized for the purpose of evaluating their affinity and sequence selectivity for duplex DNA. Competitive ethidum displacement assays indicate that 1a-1f have apparent association constants for CT DNA in the range of 1.80-16.2 × 10

Indexed as

AnimalsBinding SitesCattleDNAGentian VioletLigandsMolecular Docking SimulationStatic Electricitycalf thymus DNADNAGentian VioletLigandsB/B(∗) form DNAMajor grooveMolecular dockingNucleic acidsTriphenylmethane dyes

Identifiers

PMID30396114
PMCPMC6391077
OpenAlexW2898295760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.