Evidence map›Paper›PMID 30395992›Full record

SynthesisThe journal of allergy and clinical immunology. In practice2019

A Systematic Review of Patient- and Family-Level Inhaled Corticosteroid Adherence Interventions in Black/African Americans.

Isaretta L Riley, Beverly Murphy, Zayd Razouki, Jerry A Krishnan, Andrea Apter, Sande Okelo, Monica Kraft, Cindy Feltner, Loretta G Que, L Ebony Boulware

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in The journal of allergy and clinical immunology. In practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. The Impact of Adherence and Health Literacy on Difficult-to-Control Asthma.The journal of allergy and clinical immunology. In practice · 2022
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Isaretta L RileyDuke University School of Medicine, Durham, NC. Electronic address: isaretta.riley@duke.edu.
Beverly MurphyDuke University School of Medicine, Durham, NC.
Zayd RazoukiMayo School of Medicine, Rochester, Minn.
Jerry A KrishnanUniversity of Illinois Hospital & Health Sciences System, Chicago, Ill.
Andrea ApterPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pa.
Sande OkeloThe David Geffen School of Medicine at UCLA, Los Angeles, Calif.
Monica KraftUniversity of Arizona School of Medicine, Tuscson, Ariz.
Cindy FeltnerUniversity of North Carolina at Chapel Hill, Chapel Hill, NC.
Loretta G QueDuke University School of Medicine, Durham, NC.
L Ebony BoulwareDuke University School of Medicine, Durham, NC.

Funding

Research Project 3U54MD012530 · NIMHD · DUKE UNIVERSITY · PI JOHNSON, KIMBERLY S. · 2017 to 2022
$8.8M
NIMHD NIH HHS U54 MD012530
6 · The paper itself

Abstract

backgroundInhaled corticosteroid (ICS) adherence rates are suboptimal among adult black/African Americans. Comprehensive studies characterizing the effectiveness and the methodological approaches to the development of interventions to improve ICS adherence in adult black/African Americans have not been performed.

objectivesConduct a systematic review of patient/family-level interventions to improve ICS adherence in adult black/African Americans.

methodsWe searched MEDLINE, EMBASE, Web of Science, and CINAHL from inception to August 2017 for English-language US studies enrolling at least 30% black/African Americans comparing patient/family-level ICS adherence interventions with any comparator. Two investigators independently selected, extracted data from, and rated risk of bias. We collected information on intervention characteristics and outcomes, and assessed whether studies were informed by behavior theory, stakeholder engagement, or both.

resultsAmong 1661 abstracts identified, we reviewed 230 full-text articles and identified 4 randomized controlled trials (RCTs) and 1 quasi-experimental (pre-post design) study meeting criteria. Study participants (N range, 17-333) varied in mean age (22-47 years), proportion black/African Americans studied (71%-93%), and sex (69%-82% females). RCTs evaluated problem-solving classes, self-efficacy training, technology-based motivational interviewing program, and the use of patient advocates. The RCT testing self-efficacy training was the only intervention informed by both behavior theory and stakeholder engagement. All 4 RCTs compared interventions with active control and rated as medium risk of bias. No RCTs found a statistically significant improvement in adherence.

conclusionsFew studies assessing asthma adherence interventions focused on adult black/African-American populations. No RCTs demonstrated improved ICS adherence in participants. Future studies that are informed by behavior change theory and stakeholder engagement are needed.

Indexed as

Black or African AmericanAdministration, InhalationAdrenal Cortex HormonesAdultAsthmaCulturally Competent CareFamilyHealthcare DisparitiesHumansImplementation ScienceMedication AdherenceMotivational InterviewingPatient AdvocacyProblem SolvingReminder SystemsSelf EfficacyAdrenal Cortex HormonesAfrican AmericansAsthmaBehavior theoryCultural adaptationHealth status disparitiesImplementation scienceMedication adherence

Identifiers

PMID30395992
PMCPMC7957831

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.