Observational studyInternational journal of surgery (London, England)2018
Development of a Malawi Intensive care Mortality risk Evaluation (MIME) model, a prospective cohort study.
Observational study in International journal of surgery (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Association between prolonged Emergency Department stay and Intensive Care Unit mortality among patients at a tertiary hospital in Ethiopia.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2026Article
- Factors associated with in-hospital mortality of patients admitted to an intensive care unit in a tertiary hospital in Malawi.PloS one · 2022Article
- Predicting mortality in adults with suspected infection in a Rwandan hospital: an evaluation of the adapted MEWS, qSOFA and UVA scores.BMJ open · 2021Article
- Prevalence, Etiology, and Outcome of Sepsis among Critically Ill Patients in Malawi.The American journal of tropical medicine and hygiene · 2020Observational
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Authors and funding
5 authors.
Funding
Abstract
introductionIntensive care medicine can contribute to population health in low-income countries by reducing premature mortality related to surgery, trauma, obstetrical and other medical emergencies. Quality improvement is guided by risk stratification models, which are developed primarily within high-income settings. Models validated for use in low-income countries are needed.
methodsThis prospective cohort study consisted of 261 patients admitted to the intensive care unit (ICU) of Kamuzu Central Hospital in Malawi, from September 2016 to March 2018. The primary outcome was in-hospital mortality. We performed univariable analyses on putative predictors and included those with a significance of 0.15 in the Malawi Intensive care Mortality risk Evaluation model (MIME). Model discrimination was evaluated using the area under the curve.
resultsMales made up 37.9% of the study sample and the mean age was 34.4 years. A majority (73.9%) were admitted to the ICU after a recent surgical procedure, and 59% came directly from the operating theater. In-hospital mortality was 60.5%. The MIME based on age, sex, admitting service, systolic pressure, altered mental status, and fever during the ICU course had a fairly good discrimination, with an AUC of 0.70 (95% CI 0.63-0.76).
conclusionsThe MIME has modest ability to predict in-hospital mortality in a Malawian ICU. Multicenter research is needed to validate the MIME and assess its clinical utility.
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