Evidence map›Paper›PMID 30395772›Full record

ArticleCell cycle (Georgetown, Tex.)2018

Role of IL-17RA in the proliferative priming of hepatocytes in liver regeneration.

Danilo Piobbico, Daniela Bartoli, Stefania Pieroni, Antonella De Luca, Marilena Castelli, Luigina Romani, Giuseppe Servillo, Maria Agnese Della-Fazia

Open access · bronzeAbstract read
In one paragraph

Article in Cell cycle (Georgetown, Tex.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Liver Regeneration and Immunity: A Tale to Tell.International journal of molecular sciences · 2023
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Danilo Piobbicoa Department of Experimental Medicine , University of Perugia , Perugia , Italy.
Daniela Bartolia Department of Experimental Medicine , University of Perugia , Perugia , Italy.
Stefania Pieronia Department of Experimental Medicine , University of Perugia , Perugia , Italy.
Antonella De Lucaa Department of Experimental Medicine , University of Perugia , Perugia , Italy.
Marilena Castellia Department of Experimental Medicine , University of Perugia , Perugia , Italy.
Luigina Romania Department of Experimental Medicine , University of Perugia , Perugia , Italy.
Giuseppe Servilloa Department of Experimental Medicine , University of Perugia , Perugia , Italy.
Maria Agnese Della-Faziaa Department of Experimental Medicine , University of Perugia , Perugia , Italy.
University of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A tight link has been established between inflammation and cancer. Liver regeneration is a widely used model to study the correlation between inflammation and proliferation. IL-6 is essentially involved in liver regeneration and in cancer. Recently, IL-17A has been shown to regulate not only inflammation, but also cell proliferation. Here, we analyze the role played by IL-17A signaling in liver regeneration by comparing cell proliferation in Wild Type and IL-17RA

Indexed as

Cell ProliferationLiver RegenerationAnimalsCell CommunicationG1 Phase Cell Cycle CheckpointsHepatectomyHepatocytesInterleukin-6LiverMaleMice, Inbred C57BLMice, KnockoutReceptors, Interleukin-17Signal TransductionIl17ra protein, mouseInterleukin-6interleukin-6, mouseReceptors, Interleukin-17A20IL-17IL-17RAIL-6liver regenerationproliferation

Identifiers

PMID30395772
PMCPMC6342078
OpenAlexW2900441146

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.