Evidence map›Paper›PMID 30395729›Full record

ArticleAmerican journal of respiratory and critical care medicine2019

Pharmacologic Exhaustion of Suppressor Cells with Tasquinimod Enhances Bacterial Clearance during Tuberculosis.

Shashank Gupta, Stefanie Krug, Supriya Pokkali, Tomas Leanderson, John T Isaacs, Geetha Srikrishna, William R Bishai

Abstract readLetter
In one paragraph

Article in American journal of respiratory and critical care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. MedComm · 2023
    Review
  2. Suppressive myeloid cells in SARS-CoV-2 andFrontiers in immunology · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shashank Gupta1 Johns Hopkins University Baltimore, Maryland.
Stefanie Krug1 Johns Hopkins University Baltimore, Maryland.
Supriya Pokkali1 Johns Hopkins University Baltimore, Maryland.
Tomas Leanderson4 Lund University Lund, Sweden.
John T Isaacs1 Johns Hopkins University Baltimore, Maryland.
Geetha Srikrishna1 Johns Hopkins University Baltimore, Maryland.
William R Bishai1 Johns Hopkins University Baltimore, Maryland.

Funding

Training Program In Cellular and Molecular MedicineT32GM135457 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI RAJINI RAO · 2020 to 2026
$5.4M
PK/PD Evaluation Resistance Development in Caseating GranulomaR01AI079590 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BISHAI, WILLIAM RAMSES · 2008 to 2011
$2.5M
Targeting host immune cells and DAMP molecules to improve outcome in tuberculosisR21AI135280 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BISHAI, WILLIAM RAMSES · 2018 to 2019
$450k
Howard Hughes Medical InstituteNIAID NIH HHS R01 AI079590NIAID NIH HHS R21 AI135280NIGMS NIH HHS T32 GM135457
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsDisease Models, AnimalMiceMyeloid-Derived Suppressor CellsQuinolonesT-Lymphocytes, RegulatoryTuberculosisQuinolonestasquinimod

Identifiers

PMID30395729
PMCPMC6363972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.