Evidence map›Paper›PMID 30395594›Full record

ArticlePloS one2018

Cross-sectional study of the association between day-to-day home blood pressure variability and visceral fat area measured using the dual impedance method.

Junko Kuwabara, Koichiro Kuwahara, Yoshihiro Kuwabara, Shinji Yasuno, Yasuaki Nakagawa, Kenji Ueshima, Takeshi Kimura

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Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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7 authors.

Junko KuwabaraDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0002-0910-7483
Koichiro KuwaharaDepartment of Cardiovascular Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
Yoshihiro KuwabaraCenter for Accessing Early Promising Treatment, Kyoto University Hospital, Kyoto, Japan.ORCID 0000-0003-4161-2970
Shinji YasunoDepartment of EBM Research, Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.
Yasuaki NakagawaDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kenji UeshimaCenter for Accessing Early Promising Treatment, Kyoto University Hospital, Kyoto, Japan.
Takeshi KimuraDepartment of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe blood pressure (BP) variability (BPV) is a predictor of cardiovascular disease, independently of the BP itself. In addition, visceral fat accumulation can trigger atherosclerotic disease through various mechanisms. METHODS AND

resultsWe examined the association between fat accumulation and day-to-day BPV in 61 adult hypertensive patients. Visceral fat area (VFA) was measured using the dual bioelectrical impedance analysis method. Participants were divided into three groups based on VFA. The standard deviation (SD) in home systolic BP (SBP) for 7 consecutive days was significantly lower in the high VFA tertile (low VFA, 8.40±4.15 mmHg; intermediate VFA, 8.47±2.80 mmHg; and high VFA, 5.84±2.37 mmHg, p of One-way ANOVA = 0.017, p for trend = 0.0126). A similar association was observed between the coefficient of variance (CV) of home SBP and the VFA tertile. Multiple-regression analysis adjusted for age, sex, antihypertensive drug, diabetes, habitual drinking, and SBP level also showed a significant association between the VFA tertile and the SD or CV of home SBP. The adjusted coefficient of regression for the SD of home SBP was -3.28 (95%CI: -5.60 to -0.97, p = 0.008) and the CV of home SBP was -2.51 (95%CI: -4.31 to -0.71, p = 0.008) for the highest VFA tertile as compared to the lowest VFA tertile.

conclusionsThese results show for the first time negative correlation between VFA and day-to-day BPV. The degree of obesity should be taken into account when evaluating the value of BPV.

Indexed as

Blood PressureElectric ImpedanceIntra-Abdominal FatAgedAged, 80 and overAnalysis of VarianceBiological Variation, PopulationBiomarkersBlood Pressure DeterminationCross-Sectional StudiesFemaleHumansMaleMiddle AgedBiomarkers

Identifiers

PMID30395594
PMCPMC6218081

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