ArticleClinical spine surgery2019
Percutaneous Vertebroplasty Does Not Increase the Incidence of New Fractures in Adjacent and Nonadjacent Vertebral Bodies.
Article in Clinical spine surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Risk factors for new vertebral compression fracture following percutaneous vertebral augmentation: a systematic review and meta-analysis based on multivariate logistic regression analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Incidence of new osteoporotic adjacent vertebral body fractures. A comparison between conservative treatment and vertebral body augmentation (vertebroplasty, kyphoplasty): a systematic review and meta-analysis.Frontiers in surgery · 2025Pooled it
- Subsequent fractures after vertebroplasty in osteoporotic vertebral fractures: a meta-analysis.Neurosurgical review · 2022Pooled it
- Risk factors of vertebral re-fracture after PVP or PKP for osteoporotic vertebral compression fractures, especially in Eastern Asia: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2022Pooled it
- Vertebral CT Hounsfield units in postmenopausal women with osteoporotic vertebral compression fracture: identification and validation of reference intervals.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- To Study the Functional Outcome of Vertebroplasty versus Conservative Management in Osteoporotic Fractures.Journal of orthopaedic case reports · 2025Article
- Analysis of the impact of underlying diseases in the elderly on postoperative re-fractures after osteoporotic compression fractures.Journal of orthopaedic surgery and research · 2024Article
- Cemented vertebra and adjacent vertebra refractured in a chronic kidney disease-mineral and bone disorder patient: A case report.World journal of clinical cases · 2024Article
- The correlation between self-Hounsfield units and adjacent vertebral fracture after percutaneous vertebral augmentation: a retrospective cohort study.Quantitative imaging in medicine and surgery · 2024Article
- Occurrence of adjacent segment fractures after surgical treatment of an osteoporotic vertebral fracture: a retrospective comparison between two different treatment methods.Archives of orthopaedic and trauma surgery · 2023Article
- Clinical correlation between osteoporotic thoracolumbar vertebral compression fractures and lumbar spondylolisthesis.International orthopaedics · 2022Article
- A nomogram for short-term recurrent pain after percutaneous vertebroplasty for osteoporotic vertebral compression fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Article
- Establishment and Validation of a Nomogram for the Risk of New Vertebral Compression Fractures After Percutaneous Vertebroplasty in Patients With Osteoporotic Vertebral Compression Fractures: A Retrospective Study.Geriatric orthopaedic surgery & rehabilitation · 2022Article
- A patient with Turner syndrome received the percutaneous vertebroplasty seven times: a case report and literature review.European journal of medical research · 2021Review
- Analysis of risk factors related to the re-fracture of adjacent vertebral body after PKP.European journal of medical research · 2021Article
- Age Is Just a Number: Patient Age Does Not Affect Outcome Following Surgery for Osteoporotic Vertebral Compression Fractures.Global spine journal · 2021Article
- Males Have Higher Rates of Peri-operative Mortality Following Surgery for Osteoporotic Vertebral Compression Fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Article
- A novel and convenient method to evaluate bone cement distribution following percutaneous vertebral augmentation.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
designThis was a clinical retrospective study.
objectivesThis retrospective study aimed to investigate the incidence of new vertebral compression fractures (NVCFs) and analyze the risk factors that influence the secondary fractures in adjacent and nonadjacent levels after percutaneous vertebroplasty (PVP) and conservative treatment (CT). SUMMARY OF BACKGROUND DATA: PVP is an effective procedure to alleviate the pain caused by osteoporotic vertebral compression fractures. NVCFs have been noted as a potential late sequela of the procedure. However, it remains unclear whether NVCFs are due to this augmentation or simply are the result of the natural progression of osteoporosis.
methodsA total of 290 patients who had undergone PVP and 270 patients who had undergone CT during the last 4 years were examined. They were followed-up on a monthly basis by telephone for >2 years. They were divided into 2 groups: NVCFs and non-NVCFs. The groups were statistically compared in terms of age, sex, body mass index, initial fracture levels, bone mineral density (BMD) score of the spine, original fracture levels, and new fracture levels.
resultsAfter a mean follow-up of at least 24 months (range, 24-78 mo), 42 NVCFs occurred in 37 of 290 patients after PVP and 33 NVCFs in 30 of 270 patients after CT. Only BMD was significantly different between the groups. Lower BMD was a significant predictive factor for NVCFs.
conclusionsPVP did not increase the incidence of NVCFs, especially those adjacent to the treated vertebrae, following augmentation with PVP compared with CT. The most important risk factor for NVCFs was osteoporosis.
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Registered trials
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