Evidence map›Paper›PMID 30394470›Full record

ArticleChemical communications (Cambridge, England)2018

Evaluation of the photo-degradation of Alzheimer's amyloid fibrils with a label-free approach.

Tianke Wang, Liwei Zhang, Jie Wang, Yonghai Feng, Enquan Xu, Xiaobo Mao, Lei Liu

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Photolytic disruption of Alzheimer's amyloid AβCommunications chemistry · 2026
    Article
  2. Review
  3. Recent developments in biosensing methods for extracellular vesicle protein characterization.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2023
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tianke WangInstitute for Advanced Materials, Jiangsu University, China. liul@ujs.edu.cn.
Liwei Zhang
Jie Wang
Yonghai Feng
Enquan Xu
Xiaobo Mao
Lei Liu

Funding

Influence of Aging on Pathogenic Alpha-Synuclein Strains and Transmission MechanismK01AG056841 · NIA · JOHNS HOPKINS UNIVERSITY · PI MAO, XIAOBO · 2017 to 2021
$651k
NIA NIH HHS K01 AG056841
6 · The paper itself

Abstract

Degradation of amyloid-β (Aβ) aggregates has been considered as an attractive therapeutic and preventive strategy against Alzheimer's disease (AD). However, an in situ, real-time, and label-free technique is still lacking to understand the degradation process of Aβ aggregates. In this work, we developed a novel method to quantitatively evaluate the degradation of Aβ fibrils by photoactive meso-tetra(4-sulfonatophenyl)porphyrin under UV irradiation with quartz crystal microbalance (QCM).

Indexed as

Ultraviolet RaysAlzheimer DiseaseAmyloidHumansPhotolysisPorphyrinsProtein AggregatesQuartz Crystal Microbalance TechniquesAmyloidmeso-tetrakis(4-sulfonatophenyl)porphyrinPorphyrinsProtein Aggregates

Identifiers

PMID30394470
PMCPMC6404227

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.