Evidence map›Paper›PMID 30393831›Full record

ReviewCurrent osteoporosis reports2018

Fibula: The Forgotten Bone-May It Provide Some Insight On a Wider Scope for Bone Mechanostat Control?

J Rittweger, A Ireland, S Lüscher, L M Nocciolino, N Pilot, L Pisani, G R Cointry, J L Ferretti, R F Capozza

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current osteoporosis reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

J RittwegerDivision of Space Physiology, German Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany.
A IrelandSchool of Healthcare Science, Manchester Metropolitan University, John Dalton Building, Chester Street, Manchester, M1 5GD, UK. a.ireland@mmu.ac.uk.
S LüscherCenter of P-Ca Metabolism Studies (CEMFoC) National University of Rosario and Arg NRC (CONICET), Rosario, Argentina.
L M NocciolinoCenter of P-Ca Metabolism Studies (CEMFoC) National University of Rosario and Arg NRC (CONICET), Rosario, Argentina.
N PilotUnidad de Estudios Biomecánicos Osteo-musculares (UDEBOM), Instituto Universitario Gran Rosario (IUGR), Rosario, Argentina.
L PisaniUnidad de Estudios Biomecánicos Osteo-musculares (UDEBOM), Instituto Universitario Gran Rosario (IUGR), Rosario, Argentina.
G R CointryCenter of P-Ca Metabolism Studies (CEMFoC) National University of Rosario and Arg NRC (CONICET), Rosario, Argentina.
J L FerrettiCenter of P-Ca Metabolism Studies (CEMFoC) National University of Rosario and Arg NRC (CONICET), Rosario, Argentina.
R F CapozzaCenter of P-Ca Metabolism Studies (CEMFoC) National University of Rosario and Arg NRC (CONICET), Rosario, Argentina.
National University of Rosario · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARInstituto Universitario Italiano de Rosario · ARManchester Metropolitan University · GBUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human fibula responds to its mechanical environment differently from the tibia accordingly with foot usage. Fibula structure is unaffected by disuse, and is stronger concerning lateral bending in soccer players (who evert and rotate the foot) and weaker in long-distance runners (who jump while running) with respect to untrained controls, along the insertion region of peroneus muscles. These features, strikingly associated to the abilities of the fibulae of predator and prey quadrupeds to manage uneven surfaces and to store elastic energy to jump, respectively, suggest that bone mechanostat would control bone properties with high selective connotations beyond structural strength.

Indexed as

Stress, MechanicalBiomechanical PhenomenaBone DensityExerciseFibulaHumansdisuseexercisemechanoadaptationpQCT

Identifiers

PMID30393831
OpenAlexW2899482002

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.