Evidence map›Paper›PMID 30393493›Full record

ArticleArchives of medical science : AMS2018

Urinary neutrophil gelatinase-associated lipocalin, kidney injury molecule-1, N-acetyl-β-D-glucosaminidase levels and mortality risk in septic patients with acute kidney injury.

Heng Fan, Yu Zhao, Min Sun, Jian-Hua Zhu

Abstract read
In one paragraph

Article in Archives of medical science : AMS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  11. Role of the Furosemide Stress Test in Renal Injury Prognosis.International journal of molecular sciences · 2020
    Review
  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Heng FanDepartment of Intensive Care Unit, Ningbo First Hospital, Ningbo, China.
Yu ZhaoDepartment of Nephrology, Ningbo Urology and Nephrology Hospital, Ningbo, China.
Min SunDepartment of Intensive Care Unit, Ningbo First Hospital, Ningbo, China.
Jian-Hua ZhuDepartment of Intensive Care Unit, Ningbo First Hospital, Ningbo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of the study was to confirm whether higher levels of urinary neutrophil gelatinase-associated lipocalin (NGAL), kidney injury molecule-1 (KIM-1) and N-acetyl-β-D-glucosaminidase (NAG) are associated with mortality risk scores in severe septic patients with acute kidney injury (AKI). MATERIAL AND

methodsA prospective observational study was performed in an adult critical care unit. A total of 135 patients were included. The levels of urinary NGAL, KIM-1 and NAG were compared between patients with acute physiology and chronic health evaluation (APACHE II) score > 25 (group A,

resultsMedian level of NGAL was 105.1 ng/ml (77.6-132.5) in group A versus 40.0 ng/ml (18.6-60.5) in group B (

conclusionsIn severe septic AKI patients, high levels of NGAL, KIM-1 and NAG are associated with mortality risk scores. Urinary NGAL, KIM-1 and NAG concentrations higher than 102.5 ng/ml, 7.3 ng/ml and 15.4 U/l respectively may be used to predict increased of death risk scores.

Indexed as

acute kidney injurykidney injury molecule-1N-acetyl-β-D-glucosaminidaseneutrophil gelatinase-associated lipocalinsepsis

Identifiers

PMID30393493
PMCPMC6209703

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.