Evidence map›Paper›PMID 30393378›Full record

ArticleHypertension research : official journal of the Japanese Society of Hypertension2019

Risk of developing type 2 diabetes according to blood pressure levels and presence or absence of hypertensive treatment: the Saku study.

Yukako Tatsumi, Akiko Morimoto, Kei Asayama, Nao Sonoda, Naomi Miyamatsu, Yuko Ohno, Yoshihiro Miyamoto, Satoshi Izawa, Takayoshi Ohkubo

Abstract read
PubMed Publisher
In one paragraph

Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Hyperuricemia predicts the risk for developing hypertension independent of alcohol drinking status in men and women: the Saku study.Hypertension research : official journal of the Japanese Society of Hypertension · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yukako TatsumiDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Itabashi, Japan. y.tatsumi@med.teikyo-u.ac.jp.
Akiko MorimotoDepartment of Fundamental Nursing, Graduate School of Nursing, Osaka Prefecture University, Habikino, Japan.
Kei AsayamaDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Itabashi, Japan.
Nao SonodaDepartment of Mathematical Health Science, Graduate School of Medicine, Osaka University, Suita, Japan.
Naomi MiyamatsuDepartment of Clinical Nursing, Shiga University of Medical Science, Otsu, Japan.
Yuko OhnoDepartment of Mathematical Health Science, Graduate School of Medicine, Osaka University, Suita, Japan.
Yoshihiro MiyamotoDepartment of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Satoshi IzawaSaku Central Hospital, Saku, Japan.
Takayoshi OhkuboDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Itabashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim was to investigate the risk of developing type 2 diabetes according to blood pressure (BP) levels and presence or absence of hypertensive treatment. This 5-year cohort study comprised 3508 Japanese adults aged 30-74 years without diabetes who had undergone a medical checkup including a 75-g oral glucose tolerance test (OGTT) between April 2008 and March 2009 at Saku Central Hospital. Participants receiving antihypertensive treatment were categorized into controlled hypertension ( < 140/90 mmHg) or uncontrolled hypertension ( ≥ 140/90 mmHg) groups. Participants not receiving antihypertensive treatment were categorized: optimal BP ( < 120/80 mmHg), normal BP (120-129/80-84 mmHg), high-normal BP (130-139/85-89 mmHg), grade I hypertension (140-159/90-99 mmHg), and grade II/III hypertension ( ≥ 160/100 mmHg). Hazard ratios and 95% confidence intervals for the incidence of type 2 diabetes as defined by the 75-g OGTT were estimated using multivariable-adjusted Cox proportional hazard models in reference to optimal BP. During an average of 4.4 years of follow-up, 295 participants developed type 2 diabetes. Those with high-normal BP, grade I hypertension, grade II/III hypertension, and uncontrolled hypertension were at significantly higher risk for developing type 2 diabetes, with hazard ratios (95% confidence intervals) of 1.53 (1.03-2.29), 1.53 (1.02-2.32), 2.19 (1.01-4.77), and 1.81 (1.10-2.99), respectively. In conclusion, compared with those with optimal BP, individuals with BP ≥ 130/85 mmHg not receiving antihypertensive treatment and uncontrolled hypertensives with BP ≥ 140/90 mmHg receiving antihypertensive treatment were at a significantly higher risk for developing type 2 diabetes.

Indexed as

Blood PressureAgedAntihypertensive AgentsCohort StudiesDiabetes Mellitus, Type 2FemaleHumansHypertensionJapanMaleMiddle AgedAntihypertensive AgentsCohort studyHigh blood pressureHypertensionType 2 diabetes

Identifiers

PMID30393378

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.