ArticleMicromachines2018
3D Printing Solutions for Microfluidic Chip-To-World Connections.
Article in Micromachines, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 61 citations in OpenAlex.
- Tunable gold nanoparticle synthesis using microfluidic flow focusing enabled by reusable 3D-printed multimaterial connectors.Mikrochimica acta · 2026Article
- Augmented 3D Printing for Multiscale Microphysiological Systems.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Simple-Flow: A 3D-Printed Multiwell Flow Plate to Coculture Primary Human Lung Cells at the Air-Liquid Interface.ACS biomaterials science & engineering · 2025Article
- Polymeric Microfluidic Fuel Cells with Controlled Printed Patterns.3D printing and additive manufacturing · 2024Article
- Paper-Based Microfluidic Chips for Food Hazard Factor Detection: Fabrication, Modification, and Application.Foods (Basel, Switzerland) · 2023Review
- Parylene-C Coating Protects Resin-3D-Printed Devices from Material Erosion and Prevents Cytotoxicity toward Primary Cells.ACS applied bio materials · 2023Article
- A Review of Microfluidic Experimental Designs for Nanoparticle Synthesis.International journal of molecular sciences · 2022Review
- Wettability and Surface Roughness of Parylene C on Three-Dimensional-Printed Photopolymers.Materials (Basel, Switzerland) · 2022Article
- Silicon Nitride-Based Micro-Apertures Coated with Parylene for the Investigation of Pore Proteins Fused in Free-Standing Lipid Bilayers.Membranes · 2022Article
- A millifluidic chip for cultivation of fish embryos and toxicity testing fabricated by 3D printing technology.RSC advances · 2021Article
- Recent Advances and Future Perspectives on Microfluidic Mix-and-Jet Sample Delivery Devices.Micromachines · 2021Review
- Class II biocompatible E-Shell 300 3D printing material causes severe developmental toxicity inRSC advances · 2021Article
- Low-cost and open-source strategies for chemical separations.Journal of chromatography. A · 2021Review
- 3D Printed Microfluidic Devices for Drug Release Assays.Pharmaceutics · 2020Article
- 3D Printing of Cell Culture Devices: Assessment and Prevention of the Cytotoxicity of Photopolymers for Stereolithography.Materials (Basel, Switzerland) · 2020Article
- Rapid lipid bilayer membrane formation on Parylene coated apertures to perform ion channel analyses.Biomedical microdevices · 2020Article
- Application of Microfluidic Chip Technology in Food Safety Sensing.Sensors (Basel, Switzerland) · 2020Review
- Miniature 3D-Printed Centrifugal Pump with Non-Contact Electromagnetic Actuation.Micromachines · 2019Article
- Digital Manufacturing for Microfluidics.Annual review of biomedical engineering · 2019Review
- Polymeric Nanowires for Diagnostic Applications.Micromachines · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The connection of microfluidic devices to the outer world by tubes and wires is an underestimated issue. We present methods based on 3D printing to realize microfluidic chip holders with reliable fluidic and electric connections. The chip holders are constructed by microstereolithography, an additive manufacturing technique with sub-millimeter resolution. The fluidic sealing between the chip and holder is achieved by placing O-rings, partly integrated into the 3D-printed structure. The electric connection of bonding pads located on microfluidic chips is realized by spring-probes fitted within the printed holder. Because there is no gluing or wire bonding necessary, it is easy to change the chip in the measurement setup. The spring probes and O-rings are aligned automatically because of their fixed position within the holder. In the case of bioanalysis applications such as cells, a limitation of 3D-printed objects is the leakage of cytotoxic residues from the printing material, cured resin. This was solved by coating the 3D-printed structures with parylene-C. The combination of silicon/glass microfluidic chips fabricated with highly-reliable clean-room technology and 3D-printed chip holders for the chip-to-world connection is a promising solution for applications where biocompatibility, optical transparency and accurate sample handling must be assured. 3D printing technology for such applications will eventually arise, enabling the fabrication of complete microfluidic devices.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.