Evidence map›Paper›PMID 30392830›Full record

ArticleCell host & microbe2018

Murine Norovirus Infection Induces T

Romain Bouziat, Scott B Biering, Elaine Kouame, Kishan A Sangani, Soowon Kang, Jordan D Ernest, Mukund Varma, Judy J Brown, Kelly Urbanek, Terence S Dermody and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Cell host & microbe, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Viruses and celiac disease: what do we know ?Clinical and experimental medicine · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Early life infection withGut microbes · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Is the microbiome important in celiac disease?Journal of the Canadian Association of Gastroenterology · 2025
    Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Romain BouziatDepartment of Medicine, University of Chicago, Chicago, IL, USA; Committee on Immunology, University of Chicago, Chicago, IL, USA.
Scott B BieringCommittee on Microbiology, University of Chicago, Chicago, IL, USA.
Elaine KouameDepartment of Medicine, University of Chicago, Chicago, IL, USA; Committee on Immunology, University of Chicago, Chicago, IL, USA.
Kishan A SanganiDepartment of Medicine, University of Chicago, Chicago, IL, USA; Committee on Immunology, University of Chicago, Chicago, IL, USA.
Soowon KangDepartment of Pathology, University of Chicago, Chicago, IL, USA.
Jordan D ErnestDepartment of Medicine, University of Chicago, Chicago, IL, USA; Committee on Immunology, University of Chicago, Chicago, IL, USA.
Mukund VarmaDivision of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard University, Cambridge, MA, USA.
Judy J BrownDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
Kelly UrbanekDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Terence S DermodyDepartment of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Aylwin NgDivision of Gastroenterology, Department of Medicine, Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard University, Cambridge, MA, USA.
Reinhard HinterleitnerDepartment of Medicine, University of Chicago, Chicago, IL, USA; Committee on Immunology, University of Chicago, Chicago, IL, USA.
Seungmin HwangCommittee on Immunology, University of Chicago, Chicago, IL, USA; Committee on Microbiology, University of Chicago, Chicago, IL, USA; Department of Pathology, University of Chicago, Chicago, IL, USA. Electronic address: shwang@bsd.uchicago.edu.
Bana JabriDepartment of Medicine, University of Chicago, Chicago, IL, USA; Committee on Immunology, University of Chicago, Chicago, IL, USA; Department of Pathology, University of Chicago, Chicago, IL, USA; Section of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, University of Chicago, Chicago, IL, USA. Electronic address: bjabri@bsd.uchicago.edu.
University of Chicago · USBroad Institute · USUniversity of Pittsburgh · USVanderbilt University Medical Center · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI MARK W. LINGEN · 1985 to 2026
$122.1M
Pilot & Feasibility ProgramP30DK043351 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI RAYMOND T CHUNG · 1991 to 2026
$35.3M
MEDICAL SCIENTIST TRAININGT32GM007281 · NIGMS · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 1985 to 2022
$32.1M
ULTRASTRUCTURE AND CYTOMORPHOLOGY COREP30DK042086 · NIDDK · UNIVERSITY OF CHICAGO · PI LIU, CAMBRIAN YANGSHAO · 1990 to 2025
$29.8M
Molecular And Cellular Biology Training ProgramT32GM007183 · NIGMS · UNIVERSITY OF CHICAGO · PI GLICK, BENJAMIN S, RICE, PHOEBE A · 1985 to 2021
$23.9M
INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007090 · NIAID · UNIVERSITY OF CHICAGO · PI Peter Aidan Savage · 1985 to 2026
$11.7M
University of Chicago Initiative for Maximizing Student Development (IMSD) - Renewal 01R25GM109439 · NIGMS · UNIVERSITY OF CHICAGO · PI SCHWARTZ, NANCY B · 2014 to 2023
$5.7M
Viral infections and celiac disease pathogenesisR01DK098435 · NIDDK · UNIVERSITY OF CHICAGO · PI DERMODY, TERENCE S., JABRI, BANA · 2014 to 2022
$5.4M
Novel antiviral activity of interferon-gamma against viral replication complexR01AI127518 · NIAID · UNIVERSITY OF CHICAGO · PI RANDALL, GLENN C · 2017 to 2020
$1.6M
Targeting by autophagy proteins for anti-tumor immunityDP2CA225208 · NCI · UNIVERSITY OF CHICAGO · PI HWANG, SEUNGMIN · 2017 to 2017
$510k
NCI NIH HHS DP2 CA225208NCI NIH HHS P30 CA014599NIAID NIH HHS R01 AI127518NIAID NIH HHS T32 AI007090NIDDK NIH HHS P30 DK042086NIDDK NIH HHS P30 DK043351NIDDK NIH HHS R01 DK098435NIGMS NIH HHS R25 GM109439NIGMS NIH HHS T32 GM007183NIGMS NIH HHS T32 GM007281
6 · The paper itself

Abstract

Intestinal reovirus infection can trigger T helper 1 (T

Indexed as

DietAdministration, OralAnimalsCaliciviridae InfectionsCapsid ProteinsCeliac DiseaseDisease Models, AnimalFemaleHEK293 CellsHumansImmunityInflammationInterferon Regulatory Factor-1Lymph NodesMiceMice, Inbred C57BLCapsid ProteinsInterferon Regulatory Factor-1Irf1 protein, mouseOvalbuminceliac diseaseinflammationinterferon regulatory factor 1IRF1major capsid proteinnorovirusoral tolerancereovirusT(H)1T helper 1

Identifiers

PMID30392830
PMCPMC6326098
OpenAlexW2899293952

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.